Microbiota and Recurrent Pregnancy Loss (RPL); More than a Simple Connection
Jenny Valentina Garmendia,
Claudia Valentina De Sanctis,
Marián Hajdúch
et al.
Abstract:Recurrent Pregnancy Loss (RPL) affects 1–2% of women, and its triggering factors are unclear. Several studies have shown that the vaginal, endometrial, and gut microbiota may play a role in RPL. A decrease in the quantity of Lactobacillus crispatus in local microbiota has been associated with an increase in local (vaginal and endometrial) inflammatory response and immune cell activation that leads to pregnancy loss. The inflammatory response may be triggered by gram-negative bacteria, lipopolysaccharides (LPS)… Show more
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