Microbubble detection and ultrasound-guided vacuum-assisted biopsy of axillary lymph nodes in patients with breast cancer

Britton, P.D.; Willsher, Paula; Taylor, Kathryn M.; Kilburn‐Toppin, Fleur; Provenzano, Elena; Forouhi, Parto; Benson, John R.; Agrawal, Amit; Forman, Julia; Wallis, Matthew

doi:10.1016/j.crad.2017.03.011

Cited by 14 publications

(17 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…It explains our regular overall surgical detection rate of SLN (89.6%) . However, moderate‐to‐severe adverse effects in subsequent SLNBs have been reported in approximately 50% of patients after CEUS‐guided 13‐gauge vacuum‐assisted biopsy (VAB) of axillary SLN . The authors attributed the problem to the disruption of lymphatic drainage pathways caused by the 13‐gauge VAB cannula …”

Section: Discussionmentioning

confidence: 99%

“…There were no allergic reactions following CEUS administration and there was only one significant bleeding complication resulting in a large hematoma. Other studies recommend caution with CEUS‐guided VAB because of the risk of damage to surrounding anatomical structures . Additionally, CEUS‐guided VAB adversely affected subsequent surgical SLNB, with surgeons reporting moderate‐to‐severe interference in 48% of patients and complete failure of SLN detection in an additional 8.3% …”

Section: Discussionmentioning

confidence: 99%

“…[28][29][30] However, moderate-to-severe adverse effects in subsequent SLNBs have been reported in approximately 50% of patients after CEUS-guided 13-gauge vacuum-assisted biopsy (VAB) of axillary SLN. 38 The authors attributed the problem to the disruption of lymphatic drainage pathways caused by the 13-gauge VAB cannula. 38 A recent meta-analysis assessed complication rates after US + CNB of morphologically atypical axillary lymph nodes.…”

Section: Discussionmentioning

confidence: 99%

“…38 The authors attributed the problem to the disruption of lymphatic drainage pathways caused by the 13-gauge VAB cannula. 38 A recent meta-analysis assessed complication rates after US + CNB of morphologically atypical axillary lymph nodes. 24 Combined data from five studies showed a postprocedure complication rate of 36/502 (7.1%), with pain being the most common complication described.…”

Section: Discussionmentioning

confidence: 99%

“…39 Few studies have assessed complication rates after CEUS + CNB of sonographically normal axillary lymph nodes. 38,40 The most extensive research described the experiences of the four United Kingdom centers in the use of CEUS + CNB. 40 A total of 1361 consecutive patients were identified from a prospectively maintained database.…”

Section: Discussionmentioning

confidence: 99%

See 4 more Smart Citations

Perinodal fibrosis developed after ultrasonography‐guided core‐needle biopsy of a contrast‐enhanced ultrasound‐detected sentinel axillary node interferes with subsequent surgical sentinel node dissection

Serquiz

Moro

Menossi

et al. 2019

J of Clinical Ultrasound

View full text Add to dashboard Cite

Objective To evaluate perinodal fibrosis after 14‐gauge staging core‐needle biopsy (CNB) of the axillary sentinel lymph node (SLN) identified using contrast‐enhanced ultrasonography (CEUS) and its interference with subsequent surgical SLN dissection in breast cancer patients. Methods Frequencies or means of main clinical, sonographic, pathological, and surgical characteristics were calculated. We also compared patient groups with and without perinodal pathological fibrosis. Results Forty‐eight patients who underwent CEUS + CNB and axillary surgery were eligible for this cross‐sectional study. Axillary surgical specimens showed perinodal fibrosis in 9/48 (18.7%) patients. Interference with SLN dissection was reported in 4/48 (8.3%) patients (two hematomas, three abnormal palpation findings, and four difficult dissections). The overall surgical detection rate of SLN was 43/48 (89.6%). In the majority of cases, perinodal fibrosis was described as moderate (4/9 [44.4%]) or severe (4/9 [44.4%]). The mean time elapsed between CEUS + CNB and axillary dissection was shorter in patients with perinodal fibrosis (P = .04). Interference with SLN dissection was only reported in patients with perinodal fibrosis (P < .001). Surgical SLN detection was successful in all nine cases in which perinodal pathological fibrosis or interference with SLN dissection was reported. Conclusion Perinodal fibrosis may impair the surgical SLN dissection in early stage breast cancer patients who were staged using CEUS + CNB using a14‐gauge needle.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 3 more Smart Citations

Perinodal fibrosis developed after ultrasonography‐guided core‐needle biopsy of a contrast‐enhanced ultrasound‐detected sentinel axillary node interferes with subsequent surgical sentinel node dissection

Serquiz

Moro

Menossi

et al. 2019

J of Clinical Ultrasound

View full text Add to dashboard Cite

show abstract

Newer Modalities for the Detection and Assessment of the Sentinel Lymph Node

Karakatsanis,

Kothari

2023

Sentinel Node Biopsy in Breast Cancer

View full text Add to dashboard Cite

Axillary Nodal Staging with Contrast-Enhanced Ultrasound

Sharma

Cox

2017

Curr Breast Cancer Rep

View full text Add to dashboard Cite

Purpose of ReviewAxillary staging in the context of breast cancer is a contentious topic due to the varied practices across UK, Europe, and America. The ACOSOG Z0011 trial has questioned the role of axillary ultrasound in women with breast cancer. Published data has shown that women with ultrasound-positive lymph nodes have a worse prognosis than those with ultrasound-negative lymph nodes. Axillary ultrasound is limited as the sentinel lymph node (SLN) cannot be identified using B-mode ultrasound; however, with the advent of contrast-enhanced ultrasound (CEUS), this has now changed.Recent FindingsThe published literature has shown that the sentinel lymph node can be identified using CEUS. The rates are equivalent to blue dye alone but currently inferior to the dual technique of sentinel lymph node biopsy. There are several different contrast agents that can be used and the agents that remain in the sentinel lymph node for longer can identify areas of poor enhancement, allowing for targeted biopsy.SummaryCEUS has the potential to revolutionize the way we manage the axilla in the future and may even replace surgical staging.

show abstract

Microbubble detection and ultrasound-guided vacuum-assisted biopsy of axillary lymph nodes in patients with breast cancer

Cited by 14 publications

References 17 publications

Perinodal fibrosis developed after ultrasonography‐guided core‐needle biopsy of a contrast‐enhanced ultrasound‐detected sentinel axillary node interferes with subsequent surgical sentinel node dissection

Perinodal fibrosis developed after ultrasonography‐guided core‐needle biopsy of a contrast‐enhanced ultrasound‐detected sentinel axillary node interferes with subsequent surgical sentinel node dissection

Newer Modalities for the Detection and Assessment of the Sentinel Lymph Node

Axillary Nodal Staging with Contrast-Enhanced Ultrasound

Contact Info

Product

Resources

About