2015
DOI: 10.4172/plastic-surgery.1000917
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Microcirculatory effect of topical vapocoolants

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“…The vapocoolants may be associated with minimal erythema or blanching of the skin in some patients which resolves in \5 min [37]. An animal study that evaluated vascular and histologic changes found no significant changes with the use of Pain-Ease and concluded that it was safe [39]. One caveat to remember is that technique is critical for vapocoolant sprays to be effective.…”
Section: Needle-free Injectablesmentioning
confidence: 96%
“…The vapocoolants may be associated with minimal erythema or blanching of the skin in some patients which resolves in \5 min [37]. An animal study that evaluated vascular and histologic changes found no significant changes with the use of Pain-Ease and concluded that it was safe [39]. One caveat to remember is that technique is critical for vapocoolant sprays to be effective.…”
Section: Needle-free Injectablesmentioning
confidence: 96%