Microcomputer-based system for 24-hour recording of oesophageal motility and pH profile with automated analysis

Abstract

A system developed for long-term simultaneous recording of oesophageal motility and pH in the ambulant patient is described. The system consists of a microprocessor based data-acquisition and preprocessing device, a personal computer for postprocessing, report generation and data storage, a miniature two-sensor pressure catheter and a pH electrode. Identification and classification of oesophageal contractions are performed in separate steps, using online preprocessing software for identification and offline postprocessing software for categorisation, classification and report generation. Contractions are categorised as peristaltic, simultaneous or nontransmitte and classified according to their amplitude, duration and propagation velocity. The method described reduces the amount of data from 870 kbyte to approximately 40 kbyte per 24 hours in a multiparameter recording device, and offers the opportunity for offline postprocessing with different sets of criteria. The system has been found to be accurate and reliable in 24-hour studies in both healthy volunteers and patients with non-cardiac chest pain.

Dysphagia after nissen fundoplication

“…The system has been described in detail elsewhere [13,14]. Every contraction recorded in the 24 h study period is automatically categorized as peristaltic, simultaneous, or nontransmined [15]. Mean amplitude and duration for each contraction category were calculated separately for the upright and the supine periods, as well as for the perprandial and the interprandial periods.…”

Effects of Nissen Fundoplication on Gastro-oesophageal Reflux and Oesophageal Motor Function

“…Computerized analysis enables objective evaluation of pressure data. Oesophageal motor function in upright and supine periods and during meals can be studied separately (5,6). In this study we compared the effects of fundoplication on oesophageal acid exposure, on LOSP, and on motility of the oesophageal body, using both stationary manometry and 24-h ambulatory pH and pressure recording.…”

Data logging technology in ambulatory medical instrumentation

“…Numerous physiological, biomechanical and peripheral parameters have been data logged successfully using ambulatory monitoring, including ECG (Holter 1961), oesophageal motility and pH profile (Breedijk et al 1989), planter pressures (Zhu et al 1991), bladder pressure monitoring (Petley et al 1998) and gait-related accelerometric signals (Moe-Nilssen 1998c) amongst others. The requirements for the collection of different parameters will vary due to characteristics of the signal being recorded and the purpose of the recording, including the sampling frequency, resolution, number of channels and the recording time required.…”

“…This reduction in the required data storage capacity in conjunction with successful power management enabled the system to monitor for 24 h on a 2500 mA h 9 V source. Utilizing pre- storage processing Breedijk et al (1989) successfully compressed 870 kbytes of oesophageal motility and pH profile data to 40 kbytes allowing 24 h monitoring of one pH signal (0.125 Hz), two pressure signals (5 Hz) and two symptom indicator channels (0.125 Hz). The microprocessor based system had a capacity of 51 kbytes of SSM.…”