Microdosimetric specific energy probability distribution in nanometric targets and its correlation with the efficiency of thermoluminescent detectors exposed to charged particles

Dosimetry of the PIM1 Pion Beam at the Paul Scherrer Institute for Radiobiological Studies of Mice

“…Typical variations with respect to the Co-60 reference of .10% for LET . 1 keV/lm have been reported (19)(20)(21)(22). The charged pion beam used in this study (254 MeV/c momentum) has a LET much lower than 1 keV/lm, thus the relative efficiency of the dosimeters for the pion beam should not be underestimated by more than 10%.…”

“…Nevertheless, the relative efficiency of OSL and TLD dosimeters has been studied for different beam qualities showing a dependence of the relative efficiency as a function of LET. Typical variations with respect to the Co-60 reference of >10% for LET > 1 keV/µm have been reported ( 19 – 22 ). The charged pion beam used in this study (254 MeV/c momentum) has a LET much lower than 1 keV/µm, thus the relative efficiency of the dosimeters for the pion beam should not be underestimated by more than 10%.…”

ICRU Report 98, Stochastic Nature of Radiation Interactions: Microdosimetry

“…They are particularly well suited to microdosimetry as they can describe the stochastic nature of particle interactions and energy depositions. They have been used to characterize detectors for microdosimetry, including tissue equivalent proportional counters (TEPCs), silicon and diamond microdosimeters, and thermoluminescence detectors (TLDs), and to calculate microdosimetric quantities in radiation fields of interest (e.g., Bachiller-Perea et al , 2022; Baratto-Roldán et al , 2021; Bianchi et al , 2023; Böhlen et al , 2011; Bolst et al , 2017; 2018; 2020b; Bortot et al , 2018; Burigo et al , 2013; 2014; Conte et al , 2020; Dos Santos et al , 2020; Fattori et al , 2022; Hugtenburg et al , 2007; Kyriakou et al , 2017; Lindborg et al , 2022; Markovic et al , 2020; Matsuya et al , 2022; Mazzucconi et al , 2018; Missiaggia et al , 2023; Nikjoo et al , 1989; 1991; 1994a; 2007; Northum et al , 2012; Oliver and Thomson, 2018; Parisi et al , 2019; 2022; Petringa et al , 2020; Poignant et al , 2022a; Rollet et al , 2004; 2010; Sato et al , 2021b; Selva et al , 2022; Stewart et al , 2002; Vohradsky et al , 2021; among others).…”

“…It is interesting to note that no free parameters were used in the calculation. Using d ( z ) rather than D ( r ) , an otherwise similar approach was applied by Parisi et al (2019), who calculated relative TL efficiency of LiF: Mg, Ti and LiF:Mg,Cu,P detectors for 10 different ions from 1 H to 132 Xe over the energy range 3 to 1000 MeV/u. In the microdosimetric d ( z ) model, the author derived relative TL efficiency by folding the distribution of specific energy of the i radiation type d i ( z ) with the specific energy response function, r ( z ) , the dose response as a function of z rather than D .…”

“…Overview of the results of microdosimetric d ( z ) model for a site size of 40 nm in comparison with experimental data: (A) LiF:Mg,Ti (MTS-N) and (B) LiF:Mg,Cu,P (MCP-N) (Parisi et al , 2019). MCP-N - commercial name of LiF:Mg,Cu,P TLD detector…”