Microencapsulation of garlic oleoresin using maltodextrin as wall material by spray drying technology

Balasubramani, Priya; Palaniswamy, P T; Visvanathan, R.; Thirupathi, V.; Subbarayan, A.; Maran, J. Prakash

doi:10.1016/j.ijbiomac.2014.08.011

Cited by 88 publications

(45 citation statements)

References 21 publications

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“…The modified form very stable oil-in-water emulsions and is recommended as a total replacement for expensive encapsulating agents such as gum arabic and gelatin [20]. The characteristics of the VAP microcapsules loaded with combination of maltodextrin and modified starch matrix prepared by using spray drying technique.…”

Section: Introductionmentioning

confidence: 99%

Microencapsulation by Spray Drying of Vitamin A Palmitate from Oil to Powder and Its Application in Topical Delivery System

Gangurde¹,

Amin²

2017

JEAS

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Vitamin A palmitate (VAP) contains retinol and palmitic acid which is easily absorbed by body and widely used in skin care products. But, it is a hydrophobic and oxidation sensitive molecule which undergoes rapid degradation especially in an aqueous environment. The purpose of this study was to prepare microcapsules of VAP using combination maltodextrin and modified starches. Emulsion of VAP was prepared using cremophore RH 40 with Tween 80 in a homogenizer and formed emulsion was spray-dried. The spray process was optimized using a central composite design for two variables to obtain microcapsules with desirable characteristics. Microcapsules containing 30% of VAP were produced using different concentration of wall materials. The prepared microcapsules were evaluated for their physical, morphological, in-vitro drug release and SEM study. The results showed that obtained microcapsules are nearly spherical in shape with a particle size ranged from 1 to 12 μm. The drug content and encapsulation efficiency (53% -63%) of different batches were found within acceptable range. These stabilized drug loaded microcapsules were incorporated into silicone cream based formulation for convenient topical application and evaluated for its physicochemical parameters. The drug release study showed 80.18% to 83.43% of drug release from VAP microcapsules while topical formulations prepared by VAP microcapsules showed 67.09% to 71.45% drug release at the end of 24 hrs. The formulations were kept for 3 months stability study as per ICH guidelines and found to be stable.

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Section: Introductionmentioning

confidence: 99%

Microencapsulation by Spray Drying of Vitamin A Palmitate from Oil to Powder and Its Application in Topical Delivery System

Gangurde¹,

Amin²

2017

JEAS

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“…It consists of three interlocking 2 2 factorial designs with points lying on the surface of a sphere surrounding the center of the design. This design has been applied for several chemical and physical processes to study the effect of process variables and optimize the processes effectively (Balasubramani et al 2015).…”

Section: Introductionmentioning

confidence: 99%

Retracted: Multiple Response Analysis and Optimization of Microwave-Assisted Extraction of Antioxidant Phenolic Compounds of Waste M angifera indica L Peel

Maran¹,

Swathi²,

Jeevitha³

et al. 2015

Journal of Food Processing and Preservation

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cals, Inc. The retraction has been agreed due to evidence indicating that the peer review of this paper was compromised. It is believed that the paper was accepted based on recommendations from reviewers not suitably qualified. REFERENCE PRAKASH MARAN, J., SWATHI, K., JEEVITHA, P., JAYALAKSHMI, J. and ASHVINI, G. 2015. Multiple response analysis and optimization of microwave-assisted extraction of antioxidant phenolic compounds of waste Mangifera indica L peel.

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“…The goodness of fit of the model was evaluated by the determination co-efficient (R 2 ), adjusted determination co-efficient (R 2 a ) and co-efficient of variance (CV) and signal to noise ratio (S/N). In this study, the value of determination coefficient (R 2 = 0.962) indicated that only 0.38% of the total variations were not explained by the developed regression model [28,29]. In addition, the value of adjusted determination coefficient (R 2 a ¼ 0:927) was also very high, indicating a high significance of the model developed through experimental data [30,31].…”

Section: Rsm Modelingmentioning

confidence: 56%

Modeling of ultrasound assisted intensification of biodiesel production from neem (Azadirachta indica) oil using response surface methodology and artificial neural network

Maran¹,

Priya

2015

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Microencapsulation of garlic oleoresin using maltodextrin as wall material by spray drying technology

Cited by 88 publications

References 21 publications

Microencapsulation by Spray Drying of Vitamin A Palmitate from Oil to Powder and Its Application in Topical Delivery System

Microencapsulation by Spray Drying of Vitamin A Palmitate from Oil to Powder and Its Application in Topical Delivery System

Retracted: Multiple Response Analysis and Optimization of Microwave-Assisted Extraction of Antioxidant Phenolic Compounds of Waste M angifera indica L Peel

Modeling of ultrasound assisted intensification of biodiesel production from neem (Azadirachta indica) oil using response surface methodology and artificial neural network

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