“…There are three types of phenolic compounds and phenolic acids identified mainly in the three layers of bran (pericarp, testa, and aleurone): soluble free, soluble conjugated (glycosides), and insoluble bound states [ 26 ]. Most of the phenolic compounds from cereal bran are bonded in insoluble forms ( Figure 2 ), except in the case of rice bran, which contains more free varieties of phenolic acids [ 2 , 15 , 27 ]. Bound phenolics may only be liberated by acid (H 2 SO 4 , HNO 3 , H 3 PO 4 , and HCl), alkaline (potassium hydroxide, sodium hydroxide), or enzymatic hydrolysis by applying commercial enzymes (endoxylanase, exoxylanase, or β-glucosidase) or via fermentation bioprocesses [ 28 ].…”