During the Minnesota Children's Pesticide Exposure Study ( MNCPES ) , comparisons were made between the insecticide / herbicide loadings obtained with two household dust / insecticide or herbicide samplers: the Edwards and Lioy ( EL ) press sampler ( used for dust collection from carpets or other surfaces ) and the Lioy, Wainman and Weisel ( LWW ) surface wipe sampler. The results were compared with hand rinse levels, and urine metabolite levels obtained from 102 children ( ages 3 ± 13 ) . All measurements were made during a 1 -week sampling period, and information was obtained on household pesticide use and each child's activities. Of the homes, < 5% had recent spot uses of a pesticide but none had recent general applications. The analyses focused primarily on atrazine ( a herbicide ) , and malathion, diazinon, and chlorpyrifos ( insecticides ) . Metabolites were measured for atrazine, malathion and chlorpyrifos. The atrazine levels obtained using the EL indicate that this compound was transported into the home by an unquantified transport mechanism ( e.g. tracking of soil ) . Two malathion hand rinse values exceeded > 170 ng / cm 2 , suggesting that since indoor surface levels were low, these children had other sources of exposure. Atrazine, chlorpyrifos and malathion were detectable in > 30% of the homes by the EL, LWW or hand rinse. Only chlorpyrifos had detectable levels in !50% of the samples for all types, i.e. compound or metabolite, which is consistent with it being a common household pesticide. The median ( and maximum ) chlorpyrifos levels for the EL surface, EL carpet, LWW surface ( two rooms ) , hand rinse, and urine metabolites were: 0.07 ( 32.6 ) ng / cm 2 ; 0.07 ( 44.5 ) ng / cm 2 ; 0.34 ( 3.64 ) ng / cm 2 ; 0.42 ( 14.4 ) ng / cm 2 ; 0.03 ( 2.14 ) ng / hand and 6.9 ( 59.0 ) g / g, respectively. A strong correlation was found for chlorpyrifos between the EL surface and carpet samples. Chlorpyrifos levels detected by LWW had a different distribution and concentration range than the EL, indicating that it collected more than the surface dislodgeable insecticide. EL was directly comparable to the hand rinse or urine levels, but only the LWW had a weak correlation with hand rinse levels, suggesting that the children had other sources of chlorpyrifos exposure. Thus, mechanistic exposure studies are needed to more accurately establish exposure ± dose relationships in residential settings.