Microfluidic Device Integrated With PDMS Microchannel and Unmodified ITO Glass Electrodes for Highly Sensitive, Specific, and Point-of-Care Detection of Copper and Mercury

Mohan, Jaligam Murali; Dudala, Sohan; Amreen, Khairunnisa; Javed, Arshad; Dubey, Satish Kumar; Goel, Sanket

doi:10.1109/tnb.2023.3241827

Cited by 5 publications

(3 citation statements)

References 41 publications

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“…The LODs of Cu and Hg were 0.4 μM and 3.19 μM, respectively. 115 Santangelo et al introduced an innovative technique for the electrochemical analysis of heavy metals, which involved a graphene-based sensor integrated with a 3D-printed microfluidic chip. EG/SiC, Ag/AgCl, and Pt were used as the WE, CE, and RE, respectively.…”

Section: Microfluidic Devices For Heavy Metal Detectionmentioning

confidence: 99%

Integrated microfluidic platforms for heavy metal sensing: a comprehensive review

Nadumane,

Biswas,

Mazumder

2024

Anal. Methods

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Section: Microfluidic Devices For Heavy Metal Detectionmentioning

confidence: 99%

Integrated microfluidic platforms for heavy metal sensing: a comprehensive review

Nadumane,

Biswas,

Mazumder

2024

Anal. Methods

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“…Finally, a microfluidic device with unmodified ITO electrodes, which were formed using a CO 2 laser ablation method, has been presented for mercury detection [ 101 ]. The microchannel was made from PDMS and it was bonded via plasma with a glass containing the ITO electrodes.…”

Section: Microfluidic and Lab-on-chip Devices For Heavy Metal Ions De...mentioning

confidence: 99%

Microfluidic Devices for Heavy Metal Ions Detection: A Review

Filippidou,

Chatzandroulis

2023

Micromachines

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The contamination of air, water and soil by heavy metal ions is one of the most serious problems plaguing the environment. These metal ions are characterized by a low biodegradability and high chemical stability and can affect humans and animals, causing severe diseases. In addition to the typical analysis methods, i.e., liquid chromatography (LC) or spectrometric methods (i.e., atomic absorption spectroscopy, AAS), there is a need for the development of inexpensive, easy-to-use, sensitive and portable devices for the detection of heavy metal ions at the point of interest. To this direction, microfluidic and lab-on-chip (LOC) devices fabricated with novel materials and scalable microfabrication methods have been proposed as a promising approach to realize such systems. This review focuses on the recent advances of such devices used for the detection of the most important toxic metal ions, namely, lead (Pb), mercury (Hg), arsenic (As), cadmium (Cd) and chromium (Cr) ions. Particular emphasis is given to the materials, the fabrication methods and the detection methods proposed for the realization of such devices in order to provide a complete overview of the existing technology advances as well as the limitations and the challenges that should be addressed in order to improve the commercial uptake of microfluidic and LOC devices in environmental monitoring applications.

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“…In a distinct study, Fernández and their team employed magnetic dispersive solid-phase extraction (MDSPE) in conjunction with electrochemical detection, utilizing a screen-printed carbon electrode to determine the presence of Pb(II). In addition to lead, similar electrochemical approaches have been successfully integrated into microfluidic portable platforms for the detection of cadmium [114][115][116], mercury [117], and zinc [118]. [112] with permission from Elsevier.…”

Section: Metalmentioning

confidence: 99%

Electrochemical and Colorimetric Nanosensors for Detection of Heavy Metal Ions: A Review

Fakayode,

Walgama,

Fernand Narcisse

et al. 2023

Sensors

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Human exposure to acute and chronic levels of heavy metal ions are linked with various health issues, including reduced children’s intelligence quotients, developmental challenges, cancers, hypertension, immune system compromises, cytotoxicity, oxidative cellular damage, and neurological disorders, among other health challenges. The potential environmental HMI contaminations, the biomagnification of heavy metal ions along food chains, and the associated risk factors of heavy metal ions on public health safety are a global concern of top priority. Hence, developing low-cost analytical protocols capable of rapid, selective, sensitive, and accurate detection of heavy metal ions in environmental samples and consumable products is of global public health interest. Conventional flame atomic absorption spectroscopy, graphite furnace atomic absorption spectroscopy, atomic emission spectroscopy, inductively coupled plasma–optical emission spectroscopy, inductively coupled plasma–mass spectroscopy, X-ray diffractometry, and X-ray fluorescence have been well-developed for HMIs and trace element analysis with excellent but varying degrees of sensitivity, selectivity, and accuracy. In addition to high instrumental running and maintenance costs and specialized personnel training, these instruments are not portable, limiting their practicality for on-demand, in situ, field study, or point-of-need HMI detection. Increases in the use of electrochemical and colorimetric techniques for heavy metal ion detections arise because of portable instrumentation, high sensitivity and selectivity, cost-effectiveness, small size requirements, rapidity, and visual detection of colorimetric nanosensors that facilitate on-demand, in situ, and field heavy metal ion detections. This review highlights the new approach to low-cost, rapid, selective, sensitive, and accurate detection of heavy metal ions in ecosystems (soil, water, air) and consumable products. Specifically, the review highlights low-cost, portable, and recent advances in smartphone-operated screen-printed electrodes (SPEs), plastic chip SPES, and carbon fiber paper-based nanosensors for environmental heavy metal ion detection. In addition, the review highlights recent advances in colorimetric nanosensors for heavy metal ion detection requirements. The review provides the advantages of electrochemical and optical nanosensors over the conventional methods of HMI analyses. The review further provides in-depth coverage of the detection of arsenic (As), cadmium (Cd), chromium (Cr), copper (Cu), mercury (Hg), manganese (Mn), nickel (Ni), lead (Pb), and zinc (Zn) ions in the ecosystem, with emphasis on environmental and biological samples. In addition, the review discusses the advantages and challenges of the current electrochemical and colorimetric nanosensors protocol for heavy metal ion detection. It provides insight into the future directions in the use of the electrochemical and colorimetric nanosensors protocol for heavy metal ion detection.

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Microfluidic Device Integrated With PDMS Microchannel and Unmodified ITO Glass Electrodes for Highly Sensitive, Specific, and Point-of-Care Detection of Copper and Mercury

Cited by 5 publications

References 41 publications

Integrated microfluidic platforms for heavy metal sensing: a comprehensive review

Integrated microfluidic platforms for heavy metal sensing: a comprehensive review

Microfluidic Devices for Heavy Metal Ions Detection: A Review

Electrochemical and Colorimetric Nanosensors for Detection of Heavy Metal Ions: A Review

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