Microfluidic devices fabricated using stereolithography for preparation of monodisperse double emulsions

Kanai, Toshimitsu; Tsuchiya, Masaki

doi:10.1016/j.cej.2016.01.064

Cited by 60 publications

(38 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The devices can generate monodisperse double emulsions with three different inner droplets using three different inner channels. Moreover, the size and the number of the encapsulated droplets were precisely controlled . In summary, SL provides a relatively simplified and user‐friendly procedure for micro‐/nanostructure manufacturing without requiring lithographic masks, dies, or molds .…”

Section: Fabrication Of Micro‐/nanostructurementioning

confidence: 99%

“…Moreover, the size and the number of the encapsulated droplets were precisely controlled. [72] In summary, SL provides a relatively simplified and user-friendly procedure for micro-/nanostructure manufacturing without requiring lithographic masks, dies, or molds. [73,74] However, the acrylate-or epoxy-based photopolymers used in SL exhibit susceptibility to many commonly used organic solvents and extremes of pH, which severely limiting the applications in chemical condition.…”

Section: D Printingmentioning

confidence: 99%

See 1 more Smart Citation

Micro‐/Nanostructured Interface for Liquid Manipulation and Its Applications

Duan

Zheng

Zhao

et al. 2019

Small

View full text Add to dashboard Cite

Understanding the relationship between liquid manipulation and micro‐/nanostructured interfaces has gained much attention due to the wide potential applications in many fields, such as chemical and biomedical assays, environmental protection, industry, and even daily life. Much work has been done to construct various materials with interfacial liquid manipulation abilities, leading to a range of interesting applications. Herein, different fabrication methods from the top‐down approach to the bottom‐up approach and subsequent surface modifications of micro‐/nanostructured interfaces are first introduced. Then, interactions between the surface and liquid, including liquid wetting, liquid transportation, and a number of corresponding models, together with the definition of hydrophilic/hydrophobic, oleophilic/olephobic, the definition and mechanism of superwetting, including superhydrophobicity, superhydrophilicity, and superoleophobicity, are presented. The micro‐/nanostructured interface, with major applications in self‐cleaning, antifogging, anti‐icing, anticorrosion, drag‐reduction, oil–water separation, water collection, droplet (micro)array, and surface‐directed liquid transport, is summarized, and the mechanisms underlying each application are discussed. Finally, the remaining challenges and future perspectives in this area are included.

show abstract

Section: Fabrication Of Micro‐/nanostructurementioning

confidence: 99%

Section: D Printingmentioning

confidence: 99%

Micro‐/Nanostructured Interface for Liquid Manipulation and Its Applications

Duan

Zheng

Zhao

et al. 2019

Small

View full text Add to dashboard Cite

show abstract

“…DMD-based SL has been used to create hollow, ~ 1 mm long micro-needles (with a bore diameter of 375 μm) that could penetrate cadaveric porcine skin 22 (Figure 3B). Lately, microfluidic devices for immunomagnetic separation of bacteria 23 , separation of cells by using helical channels with trapezoid cross-sections 24 (Figure 3C), gradient generation 25 (Figure 3D), emulsion droplet generators 25-28 , DNA assembly 29 and an oxygen control insert for a 24-well dish 30 , to name a few, have been designed using single-photon SL. The minimum cross-sectional area of a microchannel that is attainable by SL depends not only on the laser spot-size or pixel resolution, but also on the type and viscosity of the resin, which has to be effectively drained from the channels post-printing 31 .…”

Section: 3d-printed Microfluidic Systems Come In Different Flavorsmentioning

confidence: 99%

The upcoming 3D-printing revolution in microfluidics

et al. 2016

View full text Add to dashboard Cite

In the last two decades, the vast majority of microfluidic systems have been built in poly(dimethylsiloxane) (PDMS) by soft lithography, a technique based on PDMS micromolding. A long list of key PDMS properties have contributed to the success of soft lithography: PDMS is biocompatible, elastomeric, transparent, gas-permeable, water-impermeable, fairly inexpensive, copyright-free, and rapidly prototyped with high precision using simple procedures. However, the fabrication process typically involves substantial human labor, which tends to make PDMS devices difficult to disseminate outside of research labs, and the layered molding limits the 3D complexity of the devices that can be produced. 3D-printing has recently attracted attention as a way to fabricate microfluidic systems due to its automated, assembly-free 3D fabrication, rapidly decreasing costs, and fast-improving resolution and throughput. Resins with properties approaching those of PDMS are being developed. Here we review past and recent efforts in 3D-printing of microfluidic systems. We compare the salient features of PDMS molding with those of 3D-printing and we give an overview of the critical barriers that have prevented the adoption of 3D-printing by microfluidic developers, namely resolution, throughput, and resin biocompatibility. We also evaluate the various forces that are persuading researchers to abandon PDMS molding in favor of 3D-printing in growing numbers.

show abstract

“…Highly monodisperse millimeter‐sized double‐emulsion droplets with tailored properties could hardly be obtained by bulk emulsification, including stirring or sonication, membrane emulsification, phase inversion, and capillary jet methods. In contrast, the droplet‐based microfluidic approach offered an incomparable degree of controlling over the size, shape, and internal structure of emulsion droplets , .…”

Section: Introductionmentioning

confidence: 99%

Production of Highly Monodisperse Millimeter‐Sized Double‐Emulsion Droplets in a Coaxial Capillary Device

et al. 2019

View full text Add to dashboard Cite

An innovative coaxial capillary device with a size-comparable outlet channel was designed to meet the challenges for controllable production of highly monodisperse millimeter-sized double-emulsion droplets by one-step dripping. The technique of two angled junctions, coaxial capillaries, and compound channel geometry was introduced to convert the millifluidics to microfluidic hydrodynamic features. The relevant nondimensional numbers for a typically regular dripping in this kind of millifluidic flows were similar to those in common microfluidic devices. Effects of the rival forces due to the fluid factors on droplet formation were clarified to explain the dynamic behaviors of double-emulsion formation and to establish the mechanism of droplet breakup. The results helped to understand the coaxial flow pattern for obtaining a more precise droplet size control and to develop high-throughput setups for chemistry, physics, and biology.

show abstract

Microfluidic devices fabricated using stereolithography for preparation of monodisperse double emulsions

Cited by 60 publications

References 22 publications

Micro‐/Nanostructured Interface for Liquid Manipulation and Its Applications

Micro‐/Nanostructured Interface for Liquid Manipulation and Its Applications

The upcoming 3D-printing revolution in microfluidics

Production of Highly Monodisperse Millimeter‐Sized Double‐Emulsion Droplets in a Coaxial Capillary Device

Contact Info

Product

Resources

About