2013
DOI: 10.1002/biot.201200386
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Microfluidic‐integrated biosensors: Prospects for point‐of‐care diagnostics

Abstract: There is a growing demand to integrate biosensors with microfluidics to provide miniaturized platforms with many favorable properties, such as reduced sample volume, decreased processing time, low cost analysis and low reagent consumption. These microfluidics-integrated biosensors would also have numerous advantages such as laminar flow, minimal handling of hazardous materials, multiple sample detection in parallel, portability and versatility in design. Microfluidics involves the science and technology of man… Show more

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Cited by 173 publications
(98 citation statements)
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“…Biosensors are becoming more important to human disease assessment and promise to revolutionize pointof-care diagnosis (Kumar et al 2013;Wang 2006). For example, the use of sensor technologies to identify biomarkers associated with wound pathology at a biochemical or cellular level has received increased attention as recently reviewed (Mohanty and Kougianos 2006).…”
Section: Introductionmentioning
confidence: 99%
“…Biosensors are becoming more important to human disease assessment and promise to revolutionize pointof-care diagnosis (Kumar et al 2013;Wang 2006). For example, the use of sensor technologies to identify biomarkers associated with wound pathology at a biochemical or cellular level has received increased attention as recently reviewed (Mohanty and Kougianos 2006).…”
Section: Introductionmentioning
confidence: 99%
“…The detection of cancer via biomarkers has been recently proposed 13. In this context, the biomarkers, such as interleukin‐8 (IL‐8), interleukin‐6 (IL‐6), vascular endothelial growth factor (VEGF) and epidermal growth factor receptor (EGFR) are currently being used for detection of oral cancer 14, 15, 16, 17.…”
Section: Introductionmentioning
confidence: 99%
“…Besides this, the testing can be performed near the vicinity of a patient and hence these devices have recently gained much attention in health care. (Gervais et al 2011;Kumar et al 2013a;Kumar et al 2013b;Luppa et al 2011) Electrochemical sensors are known to play an important role in on-going transition towards the paper based POC diagnostic devices. The electrochemical techniques offer high sensitivity, high signal-to-noise ratio, portability and fast response time.…”
Section: Introductionmentioning
confidence: 99%