2023
DOI: 10.3390/mi14101827
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Microfluidic Mixing: A Physics-Oriented Review

Sri Manikandan Saravanakumar,
Paul-Vahe Cicek

Abstract: This comprehensive review paper focuses on the intricate physics of microfluidics and their application in micromixing techniques. Various methods for enhancing mixing in microchannels are explored, with a keen emphasis on the underlying fluid dynamics principles. Geometrical micromixers employ complex channel designs to induce fluid–fluid interface distortions, yielding efficient mixing while retaining manufacturing simplicity. These methods synergize effectively with external techniques, showcasing promising… Show more

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Cited by 14 publications
(7 citation statements)
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“…Changing the channel geometry such channel’s curvature and the inner geometry, and the number of staggered/slaved structures generates different secondary flow within the channel thus influencing the mass transfer. Moreover, the height-to-width ratio of the channel cross-section affects the mean velocity [ 22 ]. All this evidence suggests that variation in microfluidic devices requires a new optimization of the manufacturing process.…”
Section: Resultsmentioning
confidence: 99%
“…Changing the channel geometry such channel’s curvature and the inner geometry, and the number of staggered/slaved structures generates different secondary flow within the channel thus influencing the mass transfer. Moreover, the height-to-width ratio of the channel cross-section affects the mean velocity [ 22 ]. All this evidence suggests that variation in microfluidic devices requires a new optimization of the manufacturing process.…”
Section: Resultsmentioning
confidence: 99%
“…The peak in the diffusion coefficient on day 2, indicating enhanced particle movement or diffusion, provides valuable insights into the mobility of nanoliposomes. This understanding can significantly impact their behavior in various applications such as drug delivery or catalysis [ 65 ].…”
Section: Discussionmentioning
confidence: 99%
“…For passive micromixers, channel geometry plays a crucial role, as the high surface-to-volume ratio inherent to microfluidic systems allows various surface properties and forces to significantly influence flow physics. Various alternative mechanisms have been explored to create disturbances and vortices so as to accelerate the mixing of two merging miscible fluids, including electrohydrodynamics, magnetohydrodynamics, and acoustofluidics [6].…”
Section: Introductionmentioning
confidence: 99%