Microfluidic paper-based fluorescence sensor for L-homocysteine using a molecularly imprinted polymer and in situ-formed fluorescent quantum dots

Assi, Navid; Rypar, Tomas; Macka, Mirek; Adam, Vojtěch; Vaculovičová, Markéta

doi:10.1016/j.talanta.2022.124185

Cited by 14 publications

(4 citation statements)

References 38 publications

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“…The microfluidic chip-based sensor with the aid of nanomaterials is a hot topic in the field of sensors, and this could be a great technique for easy analyte detection at low cost. [75][76][77] The detection of multiple target analytes simultaneously on the same platform is also possible with multiplexed sensor systems. [78][79][80] Using multiple readout strategies and utilizing properties of various nanomaterials, a few multiplexed sensors have been established in recent years and more research efforts have been made to scale up and devise innova-tive systems.…”

Section: Discussionmentioning

confidence: 99%

Plasmonic nanoparticle etching-based optical sensors: current status and future prospects

Athira,

Satija

2023

Analyst

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Section: Discussionmentioning

confidence: 99%

Plasmonic nanoparticle etching-based optical sensors: current status and future prospects

Athira,

Satija

2023

Analyst

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“…Fluorescence detection is a robust and widely utilized method in paper-microfluidics-based sensors, offering high sensitivity and specificity for detecting various analytes [ 110 , 111 , 112 , 113 , 114 ]. This approach capitalizes on the innate fluorescence properties of specific molecules known as fluorophores, facilitating target substances’ precise identification and quantification.…”

Section: Detection Techniquesmentioning

confidence: 99%

Sustainable Sensing with Paper Microfluidics: Applications in Health, Environment, and Food Safety

Kumar,

Kaushal,

Lee

2024

Biosensors

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This manuscript offers a concise overview of paper microfluidics, emphasizing its sustainable sensing applications in healthcare, environmental monitoring, and food safety. Researchers have developed innovative sensing platforms for detecting pathogens, pollutants, and contaminants by leveraging the paper’s unique properties, such as biodegradability and affordability. These portable, low-cost sensors facilitate rapid diagnostics and on-site analysis, making them invaluable tools for resource-limited settings. This review discusses the fabrication techniques, principles, and applications of paper microfluidics, showcasing its potential to address pressing challenges and enhance human health and environmental sustainability.

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“…Cloth Luminol functionalized gold nanoparticles 0.02 fM Electrochemiluminescence Wu et al [76] L-homocysteine Wine solution Paper Fluorescent quantum dots 0.51 μM Fluroscent Assi et al [77] Flow tests…”

Section: Human Liver Cellular Homogenatementioning

confidence: 99%

Enhancement in the limit of detection of lab‐on‐chip microfluidic devices using functional nanomaterials

2023

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Technological developments in recent years have witnessed a paradigm shift towards lab‐on‐chip devices for various diagnostic applications. Lab‐on‐chip technology integrates several functions typically performed in a large‐scale analytical laboratory on a small‐scale platform. These devices are more than the miniaturized versions of conventional analytical and diagnostic techniques. The advances in fabrication techniques, material sciences, surface modification strategies, and their integration with microfluidics and chemical and biological‐based detection mechanisms have enormously enhanced the capabilities of these devices. The minuscule sample and reagent requirements, capillary‐driven pump‐free flows, faster transport phenomena, and ease of integration with various signal readout mechanisms make these platforms apt for use in resource‐limited settings, especially in developing and underdeveloped parts of the world. The microfluidic lab‐on‐a‐chip technology offers a promising approach to developing cost‐effective and sustainable point‐of‐care testing applications. Numerous merits of this technology have attracted the attention of researchers to develop low‐cost and rapid diagnostic platforms in human healthcare, veterinary medicine, food quality testing, and environmental monitoring. However, one of the major challenges associated with these devices is their limited sensitivity or the limit of detection. The use of functional nanomaterials in lab‐on‐chip microfluidic devices can improve the limit of detection by enhancing the signal‐to‐noise ratio, increasing the capture efficiency, and providing capabilities for devising novel detection schemes. This review presents an overview of state‐of‐the‐art techniques for integrating functional nanomaterials with microfluidic devices and discusses the potential applications of these devices in various fields.

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Microfluidic paper-based fluorescence sensor for L-homocysteine using a molecularly imprinted polymer and in situ-formed fluorescent quantum dots

Cited by 14 publications

References 38 publications

Plasmonic nanoparticle etching-based optical sensors: current status and future prospects

Plasmonic nanoparticle etching-based optical sensors: current status and future prospects

Sustainable Sensing with Paper Microfluidics: Applications in Health, Environment, and Food Safety

Enhancement in the limit of detection of lab‐on‐chip microfluidic devices using functional nanomaterials

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