Microfluidics Engineering: Recent Trends, Valorization, and Applications

Abstract

In recent years, microfluidics engineering has gained increasing research interests in assimilation and designing novel constructs for various application in bio-and non-bio sectors of the modern world. Soft and photo-lithographic fabricated devices have a potential to control the diffusion and flow of liquids in channels. The fabricated microfluidic devices of unique geometry facilitate excellent control over extracellular microenvironment and soluble factor interactions. The current devices do not only replace the in-vitro approaches but also provide a new understanding of biomolecules separation and flow in the network of microchannels. The appropriate physiological responses of cells in biological studies or drug screening analysis require engineering of active cells outside the body to enhance their maximum potential for best cellular therapy. This review work mainly focuses on the current methodologies involved in the fabrication process and limitations of cell array technology. The information is given on considerable advantages of microfluidic devices. Towards the end, potential applications covering microfluidic-based in-vitro drug analysis and analytical-based separation/detachment are discussed with potential future viewpoints.

Photocatalytic Activity of Carbon Nanotubes Synthesized by Flame Fragments Deposition Method and Its Composites with TiO2

“…The peak at 1581 cm -1 in the spectrum for carbon nanotubes relates to G-band of graphitic carbon in carbon nanotubes while D-and G-groups show the nearness of crystalline graphite carbon in carbon nanotubes. The G′ band at 2700 cm -1 are sensitive to the freight exchanged between the nanotubes and the demote moiety [20]. Crystal structure of carbon nanotubes was investigated using XRD patterns using (Rigaku Rotalflex) (RU-200B) Xray diffractometer with CuKα radiation (λ = 0.15405 nm) with a Ni filter.…”

Advancements and Potential Applications of Microfluidic Approaches—A Review

“…With an extensive series of daily life applications, the fabrication of devices is considered an emerging technology, stabilizing various micro-machining techniques, soft and polymer-based lithography such as PDMS devices. Moreover, the assimilation of multi-functional Micro Electro Mechanical Systems (MEMS) devices: Micropumps and valves as well as other dynamic mixers [55,56]. The active and passive mixing flow the integration of mini-actuators can easily achieve velocity and control over the reagents into microchannels.…”

“…Traditional approaches to analyze antibiotic resistance are comprised of disk diffusion and broth dilution methods [99]. Microfluidic devices can develop infectious diseases management at point-of-care as well as the implementation of antimicrobial susceptibility test (AST) at clinics [55,100]. An essential condition for the prompt growth of bacterial species is the sufficient availability of oxygen in the microenvironment [101].…”

Microfluidic Advancements in Classical Biotechnology – A Review

“…With an extensive series of daily life applications, the fabrication of devices is considered as an emerging technology, stabilising various micro-machining techniques, soft and polymer-based lithography such as PDMS devices. Moreover, the assimilation of multi-functional Micro Electro Mechanical Systems (MEMS) devices: micropumps and valves as well as other dynamic mixers [55,56]. The active and passive mixing flow the integration of mini-actuators can easily achieve velocity and control over the reagents into microchannels.…”

“…Traditional approaches for analysing antibiotic resistance comprises of disk diffusion and broth dilution methods [99]. Microfluidic devices have the capability to develop infectious diseases management at point-of-care as well as the implementation of antimicrobial susceptibility test (AST) at clinics [55,100]. An essential condition for the prompt growth of bacterial species is the availability sufficient oxygen in the microenvironment [101].…”