Microfluidics in environmental analysis: advancements, challenges, and future prospects for rapid and efficient monitoring

Aryal, Prakash; Hefner, Claire; Martinez, Brandaise; Henry, Charles S.

doi:10.1039/d3lc00871a

Cited by 19 publications

(3 citation statements)

References 305 publications

(310 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…All the inherent advantages of aptasensors position them favorably for the design of user-friendly and portable devices for in-field analyses. Indeed, (micro)fluidic approaches have gained wide interest as a tool in the automation of sample collection and handling, allowing for on-line and continuous measurements [114,115]. New smartphone-assisted platforms or other compact analyzers based on colorimetric and electrochemical readouts have been introduced in recent years [116,117].…”

Section: Scalabilitymentioning

confidence: 99%

Aptasensors for the Detection of Environmental Contaminants of High Concern in Water Bodies: A Systematic Review

Reynoso,

Sfragano,

González-Perea

et al. 2024

Chemosensors

View full text Add to dashboard Cite

With the advancement of technology and increasing industrial activity, anthropogenic contaminants are currently detected where there is no record of their presence or insufficient information about their toxicological impact. Consequently, there are not sufficiently robust local or global regulations, the ecotoxicological and human health risks are critical, and they may not be routinely monitored despite being ubiquitous. The interest in studying environmental contaminants, including micropollutants and emerging contaminants, in complex environmental water samples has grown in the last decade. Due to the concentrations in which they are typically found in the environment and the rapid global dispersion, the detection procedures for these substances must be capable of measuring very low concentrations. Many efforts have been made to improve remediation procedures or develop novel analytical methods for their determination. Although there are several robust and reliable standard analytical techniques for their monitoring, pollutant contamination requires simple and inexpensive methods for massive, in situ monitoring campaigns. In this regard, biosensors have emerged as devices with high selectivity, sensitivity, easy operation, and short analysis times. Aptasensors are biosensors based on a nucleic acid recognition element (aptamer). Due to their synthetic nature, stability, and easy production, aptamers are frequently employed to develop bioassays. This work presents a systematic review of the trends in using aptasensors for detecting environmental contaminants present in environmental water samples, as well as the estimation of the potential technological contribution these devices might give to environmental monitoring.

show abstract

Section: Scalabilitymentioning

confidence: 99%

Aptasensors for the Detection of Environmental Contaminants of High Concern in Water Bodies: A Systematic Review

Reynoso,

Sfragano,

González-Perea

et al. 2024

Chemosensors

View full text Add to dashboard Cite

show abstract

“…Paper-based analytical devices (PADs) exhibit a wide range of approaches in modern chemical analysis, ranging from simple and cost-effective low-tech versions to sophisticated ones. 26 The combination of low cost, widespread availability, simple fabrication, and biodegradability inherent in these paper-based systems renders them suitable for point-of-care testing in resource-limited environments. 26–28…”

Section: Introductionmentioning

confidence: 99%

“…26 The combination of low cost, widespread availability, simple fabrication, and biodegradability inherent in these paper-based systems renders them suitable for point-of-care testing in resource-limited environments. 26–28…”

Section: Introductionmentioning

confidence: 99%

Non-invasive iron deficiency diagnosis: a saliva-based approach using capillary flow microfluidics

Prakobdi,

Baldo,

Aryal

et al. 2024

Anal. Methods

Self Cite

View full text Add to dashboard Cite

show abstract

Integration of microfluidic chips with biosensors

Sekhwama,

Mpofu,

Sudesh

et al. 2024

Discov Appl Sci

View full text Add to dashboard Cite

The potential threat posed by disease outbreaks to diagnostic instruments demands the development of more effective biosensor technologies to counteract the risks. Diseases like SARS-CoV-2, Ebola, malaria, cholera, and many more have demonstrated beyond the limits of health care that new advancements are required for early detection and diagnosis. The rising number of diseases outbreaks has led to an increasing demand for biosensors that are more effective and quicker to utilize in healthcare settings. A biosensor incorporated with microfluidic chips offers an improved detection compared to traditional or classical biosensors. Microfluidic chips improve the performance of the biosensors by allowing automation, mixing, separation, throughput processing, and transport of the analytes to desired reactors. A biosensor incorporated with a microfluidic chip has improved sensitivity, easy operation and can use small volumes of samples to process the results. The effectiveness of biosensors depends also on the materials used in its fabrication and there are many materials used for fabrication which are reviewed in this work. This paper reviews the potential advantages of the use of microfluidic chips to enhance the performance of biosensors, materials used to fabricate the chips, and potential electrodes incorporated into microfluidic chips which improve the detection time by shortening the processing time for biosensors at the point of care service. This work also reviews new technologies which are not previously addressed other reviews including, integration of cell-imprinted polymers with microfluidic sensors and delved into future technologies outlook.

show abstract

Microfluidics in environmental analysis: advancements, challenges, and future prospects for rapid and efficient monitoring

Abstract: This review highlights the latest advancements in microfluidic devices in environmental monitoring during the last 5 years. We also emphasize the current limitations in the devices and propose effective strategies to improve environmental monitoring.

Cited by 19 publications

References 305 publications

Aptasensors for the Detection of Environmental Contaminants of High Concern in Water Bodies: A Systematic Review

Aptasensors for the Detection of Environmental Contaminants of High Concern in Water Bodies: A Systematic Review

Non-invasive iron deficiency diagnosis: a saliva-based approach using capillary flow microfluidics

Integration of microfluidic chips with biosensors

Contact Info

Product

Resources

About