Microfracture for Osteochondral Lesions of the Ankle: Outcome Analysis and Outcome Predictors of 105 Cases

Chuckpaiwong, Bavornrit; Berkson, Eric M.; Theodore, George H.

doi:10.1016/j.arthro.2007.07.022

Cited by 417 publications

(480 citation statements)

References 33 publications

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“…82,149,235,457 Asymptomatic or low-symptomatic lesions are treated nonoperatively by rest, ice, temporarily reduced weight bearing, and an orthosis in case of giving way, for a trial period of 6 months. 346,457 Although nonoperative therapy yields only 45% successful results, 439 a trial period does not adversely affect the outcome of surgery.…”

Section: Discussionmentioning

confidence: 99%

“…343 Full return to normal and sporting activities is usually possible 4 to 6 months after surgery. 82 …”

Section: Rehabilitationmentioning

confidence: 99%

“…Although often successful, this may be insufficient for large defects. 82 Preoperatively, the approach to the defect should be determined (see Surgical approach section). In the case of arthroscopic treatment it has to be decided whether to use a 4.0-mm arthroscope and treat the OCD in the anterior working area by full plantar flexion of the ankle, or to use a 2.7-mm arthroscope in combination with mechanical distraction.…”

Section: Debridement and Bone Marrow Stimulationmentioning

confidence: 99%

“…393,439 In larger (cystic) defects this treatment is less successful, and hence there is more debate. 82,149 Th e aim of this article is to provide an overview of treatment options and their indications for OCDs of the talus, based on the current evidence.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Treatment of osteochondral defects of the talus

Bergen

Leeuw

Dijk

2008

Revue de Chirurgie Orthopédique et Réparatrice de l'Appareil Mo

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Section: Discussionmentioning

confidence: 99%

“…343 Full return to normal and sporting activities is usually possible 4 to 6 months after surgery. 82 …”

Section: Rehabilitationmentioning

confidence: 99%

Section: Debridement and Bone Marrow Stimulationmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Treatment of osteochondral defects of the talus

Bergen

Leeuw

Dijk

2008

Revue de Chirurgie Orthopédique et Réparatrice de l'Appareil Mo

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“…Current indication to proceed with either BMS or AOT is primarily based on the size of the lesion. It is traditionally accepted that smaller lesions up to 150 mm 2 in size or 15 mm in diameter are treated with BMS [8,9] and larger lesions are treated with AOT [10]. In addition, there has been recent evidence recommending AOT for the treatment after failed BMS [11].…”

Section: Operative Treatmentmentioning

confidence: 99%

Osteochondral lesions of the talus in the athlete: up to date review

Shimozono

Yasui

Ross

et al. 2017

Curr Rev Musculoskelet Med

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Purpose of review Osteochondral lesions of the talus (OLT) are common injuries in athletes. The purpose of this study is to comprehensively review the clinical results and return to sport capacity in athletes following treatment for OLT. Recent findings Reparative procedures, such as bone marrow stimulation, and replacement procedures, such as autologous osteochondral transplantation, provide good clinical outcomes in short-and mid-term follow-up in the athlete. Recently, biological augmentation and scaffold-based therapies have been shown to improve clinical and radiological outcomes in OLT in both the general population and athletes. Summary Most studies are of a low level of evidence. Studies analyzing the return to sport capability in athletes are further lacking. High-level evidence and well-designed clinical trials are required to establish the most effective treatment protocol.

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Evaluation of tissue integration of injectable, cell‐laden hydrogels of cocultures of mesenchymal stem cells and articular chondrocytes with an ex vivo cartilage explant model

Kim

Mehta

Guo

et al. 2021

Biotech & Bioengineering

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This study investigated the chondrogenic activity of encapsulated mesenchymal stem cells (MSCs) and articular chondrocytes (ACs) and its impact on the mechanical properties of injectable poly(N-isopropylacrylamide)-based dual-network hydrogels loaded with poly(L-lysine) (PLL). To this effect, an ex vivo study model was employed to assess the behavior of the injected hydrogels-specifically, their surface stiffness and integration strength with the surrounding cartilage. The highest chondrogenic activity was observed from AC-encapsulated hydrogels, while the effect of PLL on MSC chondrogenesis was not apparent from biochemical analyses. Mechanical testing showed that there were no significant differences in either surface stiffness or integration strength among the different study groups. Altogether, the results suggest that the ex vivo model can allow further understanding of the relationship between biochemical changes within the hydrogel and their impact on the hydrogel's mechanical properties.

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Microfracture for Osteochondral Lesions of the Ankle: Outcome Analysis and Outcome Predictors of 105 Cases

Cited by 417 publications

References 33 publications

Treatment of osteochondral defects of the talus

Treatment of osteochondral defects of the talus

Osteochondral lesions of the talus in the athlete: up to date review

Evaluation of tissue integration of injectable, cell‐laden hydrogels of cocultures of mesenchymal stem cells and articular chondrocytes with an ex vivo cartilage explant model

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