Microgels by intramolecular crosslinking of poly(allylamine) single chains

Pulses of Fast Electrons as a Tool To Synthesize Poly(acrylic acid) Nanogels. Intramolecular Cross-Linking of Linear Polymer Chains in Additive-Free Aqueous Solution

“…Similar differences in the swelling properties of linear and internally cross-linked macromolecules in response to changes in salt concentration have been reported for nanogels of a cationic polyelectrolyte, poly(allylamine). 26 Degradation Resistance. One of the most valuable properties of nanogels is their enhanced resistance against degradation.…”

“…It has been shown that intramolecular cross-linking of single chains of water-soluble polymers can be carried out by reacting them with a suitable cross-linking agent in dilute solutions. , Recently, we have proposed an alternative method, where neither cross-linker nor any other additive is necessary . In this approach, discussed in more detail below, a pure aqueous solution of a polymer is subjected to a short (a few microseconds) intense pulse of ionizing radiation.…”

Intramolecular Cross-Linking Methodologies for the Synthesis of Polymer Nanoparticles

“…Other early examples of intramolecularly cross-linked polymers involved the synthesis of water-soluble microgels. Frank and Burchard reported single-chain microgels containing free amino groups as model of living cells to study the interaction with polysaccharides . The authors chose water-soluble poly­(allylamine) (PALA) as the precursor polymer.…”

Synthesis and characterisation of thermo-responsive poly(N,N′-diethylacrylamide) microgels

“…Four methods have been reported for the preparation of microgel particles, namely emulsion polymerisation [15][16][17][18], anionic copolymerisation [19], cross-linking of neighbouring polymer chains [20,21], and inverse micro-emulsion polymerisation [22,23]. Emulsion polymerisation can be performed in the presence of a surfactant [17,[24][25][26][27][28] or as Surfactant-Free Emulsion Polymerisation (SFEP), also called precipitation polymerisation [12,[29][30][31][32].…”