The question of how to simultaneously perform frequency regulation and integrated economic scheduling for microgrids with low-inertia islanding operation under communication constraints is a difficult problem that needs to be solved for many current applications. To this end, this paper establishes a microgrid scheduling control model containing a virtual synchronous generator (VSG) with multiple types of power sources and proposes a distributed optimization algorithm that integrates frequency regulation and comprehensive economic scheduling to simultaneously realize frequency regulation and economic scheduling in a microgrid. Firstly, a distributed economic dispatch problem is proposed based on a comprehensive consideration of the costs and benefits of various types of power VSGs, as well as the overall inertia and standby capacity requirements of the microgrid, which minimizes the integrated costs incurred by the participation of each type of VSG in the frequency regulation and improves the stable operation of the microgrid in terms of frequency under perturbation. Then, the optimal scheduling problem is solved by reconstructing the optimization problem based on considering the dynamic characteristics of microgrid inverters and using event-triggered communication to sense and compensate for the supply-demand imbalance online. The proposed method can avoid inter-layer coordination across time scales, improve the inertia, frequency regulation capability, and economy of the system, and enhance its robustness to short-term communication failures. Finally, simulation results are used to verify the effectiveness of the method.