Microinvasive carcinoma of the cervix

Nagell, J.R. van; Greenwell, N.; Powell, D.F.; Donaldson, Elvis S.; Hanson, M.

doi:10.1016/0002-9378(83)90852-9

Cited by 116 publications

(46 citation statements)

References 8 publications

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“…Nevertheless, some have adopted the presence of LVI, or ''extensive'' LVI, as an exclusion criterion for conservative management [105,110,111,134]. In contrast, there is an increased prevalence of both lymph node metastases and recurrence after local excision in FIGO IA2, and many studies conclude that local excision alone is inadequate for this group of patients [39,103,118,126,128,130,[134][135][136][137][138].…”

Section: Site-specific Recommendationsmentioning

confidence: 99%

The Lower Anogenital Squamous Terminology Standardization Project for HPV-Associated Lesions: Background and Consensus Recommendations from the College of American Pathologists and the American Society for Colposcopy and Cervical Pathology

Darragh

Colgan

Cox

et al. 2012

Archives of Pathology &Amp; Laboratory Medicine

643

372

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The terminology for human papillomavirus (HPV)–associated squamous lesions of the lower anogenital tract has a long history marked by disparate diagnostic terms derived from multiple specialties. It often does not reflect current knowledge of HPV biology and pathogenesis. A consensus process was convened to recommend terminology unified across lower anogenital sites. The goal was to create a histopathologic nomenclature system that reflects current knowledge of HPV biology, optimally uses available biomarkers, and facilitates clear communication across different medical specialties. The Lower Anogenital Squamous Terminology (LAST) Project was cosponsored by the College of American Pathologists and the American Society for Colposcopy and Cervical Pathology and included 5 working groups; 3 work groups performed comprehensive literature reviews and developed draft recommendations. Another work group provided the historical background and the fifth will continue to foster implementation of the LAST recommendations. After an open comment period, the draft recommendations were presented at a consensus conference attended by LAST work group members, advisors, and representatives from 35 stakeholder organizations including professional societies and government agencies. Recommendations were finalized and voted on at the consensus meeting. The final, approved recommendations standardize biologically relevant histopathologic terminology for HPV-associated squamous intraepithelial lesions and superficially invasive squamous carcinomas across all lower anogenital tract sites and detail the appropriate use of specific biomarkers to clarify histologic interpretations and enhance diagnostic accuracy. A plan for disseminating and monitoring recommendation implementation in the practicing community was also developed. The implemented recommendations will facilitate communication between pathologists and their clinical colleagues and improve accuracy of histologic diagnosis with the ultimate goal of providing optimal patient care.

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Section: Site-specific Recommendationsmentioning

confidence: 99%

The Lower Anogenital Squamous Terminology Standardization Project for HPV-Associated Lesions: Background and Consensus Recommendations from the College of American Pathologists and the American Society for Colposcopy and Cervical Pathology

Darragh

Colgan

Cox

et al. 2012

Archives of Pathology &Amp; Laboratory Medicine

643

372

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“…2), 10 lymph node metastasis (Figs. 3, 4; Table 2), 11,12 lymphatic vascular space invasion (Table 3), [13][14][15][16][17][18][19][20] deep stromal invasion (Table 4), [21][22][23][24][25][26] microscopic evidence of parametrial extension, cell type ( Fig. 5), 27 and hemoglobin level.…”

Section: Stagingmentioning

confidence: 99%

“…Van Nagell et al 21 32 3 (9.4%) 3 2 Hasumi et al 22 29 4 (13.8%) NS NS Simon et al 23 26 1 (3.8%) 0 0 Maiman et al 24 30 4 (13.3%) 0 0 Buckley et al 25 94 7 (7.4%) 5 4 Creasman et al 26 51 Reprinted from Eifel et al 27 (Adenocarcinoma as an independent risk factor for disease recurrence in patients with Stage IB cervical carcinoma. Gynecol Oncol.…”

Section: Dead Of Diseasementioning

confidence: 99%

Imaging in cervical cancer

Follen

Levenback

Iyer

et al. 2003

Cancer

129

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“…The incidence of positive nodes in patients with stage I A1 disease has been reported to be 0.5-0.8% 17,18) . The overall incidence of lymph node metastases in patients with depth of invasion of 3-5 mm has been reported as 7.1%, although this varies from 0% to 13.8% 15,[19][20][21][22][23] . Patients with 3-5 mm of invasion present at conization and with no invasion in the hysterectomy specimen are at very low risk for lymph node metastases, recurrence, or death that is caused by the cancer 15) .…”

Section: Methodsmentioning

confidence: 99%

Surgical Treatment Outcomes in Patients with Stage pT1a and pT1b1 Cervical Cancer

Takeuchi

2007

J Rural Med

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Objective : The object of this study was to assess the outcomes of surgical treatment of stage pT1a and pT1b1 cervical cancer. Method Conclusion :The results suggest that the surgical procedure did not affect prognosis in the cases we analyzed by surgical modalities. The current evidence suggests that a patient in an early stage can undergo less aggressive surgery than the current operative modality requires.

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Microinvasive carcinoma of the cervix

Cited by 116 publications

References 8 publications

The Lower Anogenital Squamous Terminology Standardization Project for HPV-Associated Lesions: Background and Consensus Recommendations from the College of American Pathologists and the American Society for Colposcopy and Cervical Pathology

The Lower Anogenital Squamous Terminology Standardization Project for HPV-Associated Lesions: Background and Consensus Recommendations from the College of American Pathologists and the American Society for Colposcopy and Cervical Pathology

Imaging in cervical cancer

Surgical Treatment Outcomes in Patients with Stage pT1a and pT1b1 Cervical Cancer

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