Micronutrient deficiencies in inflammatory bowel disease

Weisshof, Roni; Chermesh, Irit

doi:10.1097/mco.0000000000000226

Cited by 200 publications

(168 citation statements)

References 50 publications

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“…A lack of iron is present in 30% to 90% of anemic IBD patients [16] and zinc deficiency is associated with a poor disease outcome and a higher risk for disease-related complications [52]. The daily intake of these minerals, as well as of potassium and magnesium, was in accordance with the recommendations of DACH in all our study participants.…”

Section: Food Group Hc Total Ibd Ibd (Intake In [G/d]) CD Ucmentioning

confidence: 55%

“…Summarizing the use of vitamins (6%), minerals (4%) and combinations (15%) of the IBD patients in our study the prevalence was 25% and confirmed former results. Since micronutrients deficiencies were described in over 50% of IBD patients [16], it is highly recommended to monitor the vitamin and micronutrient status and apply dietary supplementation to prevent or treat deficiencies.…”

Section: Food Group Hc Total Ibd Ibd (Intake In [G/d]) CD Ucmentioning

confidence: 99%

“…Especially the omission of certain fruits, vegetables or dairy without professional dietary advice can contribute to an insufficient intake of vitamins and minerals. Since patients with IBD often present with various micronutrient deficiencies, particularly for iron, calcium, zinc or vitamin B12, folate and vitamin D, an inadequate nutrition might further impair the progression of the disease [16]. In consequence, complications of micronutrient deficiencies, including anemia and osteoporosis, are often diagnosed and are associated with a poor disease outcome, growth retardation in children, longer hospitalization time and increased morbidity [17].…”

Section: Introductionmentioning

confidence: 99%

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Dietary Habits and Nutrient Intake in Patients with Inflammatory Bowel Disease

Schink¹,

Mirsch²,

Dieterich³

et al. 2017

J Nutr Food Sci

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Patients with inflammatory bowel diseases (IBD) are often affected by nutrient deficiencies. Besides a limited nutrient intake by disease-related side effects and malabsorption, the influence of diets and dietary changes is much discussed. However, data about food patterns are mostly based on subjective declarations. Therefore, this study aimed to achieve a detailed and objective analysis of nutrient intake and individual food habits in IBD, a prerequisite for an appropriate nutritional intervention in risk patients. One hundred IBD patients (n=70 Crohn's disease (CD), n=30 ulcerative colitis (UC)) and 30 healthy controls (HC) were included in the study. All participants filled in a disease-related and food frequency questionnaire. Fifteen healthy controls and 71 IBD patients additionally completed a questionnaire for self-imposed food restrictions. Most IBD patients and healthy controls showed a normal body mass index. However, within the IBD group, UC patients were more often overweight than CD patients (p=0.007). Food restrictions were common in all participants, but significantly more IBD patients restricted their consumption of fast food (p=0.037), fruits and vegetables (p=0.019). Especially CD patients with acute relapse consumed less fruits and vegetables (p=0.035). Contrary to subjective assessment, an objective survey of dietary intake revealed a significantly higher sugar intake of IBD patients compared to healthy controls (p<0.001) with an increased ingestion of sugar/confectionery (p=0.041), soft/isotonic drinks (p<0.001) and fruit/vegetable juices (p=0.022). Additionally, IBD patients ingested higher amounts of salt than healthy controls (p=0.005). Both groups showed an insufficient ingestion of folate, vitamin D and pantothenic acid.In conclusion, self-managed food restrictions appear to be common in IBD patients. The huge discrepancy between the subjective view of dietary habits and objective evaluation of nutrient intake indicates that nutrient assessment should be based on objective tools. A repetitive professional nutritional counseling is recommended to prevent and treat nutritional deficiencies.

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Section: Food Group Hc Total Ibd Ibd (Intake In [G/d]) CD Ucmentioning

confidence: 55%

Section: Food Group Hc Total Ibd Ibd (Intake In [G/d]) CD Ucmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Dietary Habits and Nutrient Intake in Patients with Inflammatory Bowel Disease

Schink¹,

Mirsch²,

Dieterich³

et al. 2017

J Nutr Food Sci

View full text Add to dashboard Cite

show abstract

“…This may vary from only mild alterations in trace elements to severe malnutrition with great weight loss due to the involvement of the gastroin-testinal tract and its effects on food intake and absorption. 4,[22][23][24] Malnutrition is especially common in active UC patients after long-term hospitalization; 11,25 however, few studies have evaluated the nutritional status in patients with UC during remission. 4,12,26,27 Only one trial found a more compromised nutritional status (body weight and BMI) in UC patients during remission than in a control group.…”

Section: Discussionmentioning

confidence: 99%

Associations among body composition, inflammatory profile and disease extent in ulcerative colitis patients

Urbano

Sassaki

Dorna

et al. 2018

Rev. Assoc. Med. Bras.

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Objective: The aim of our study was to assess body composition status and its association with inflammatory profile and extent of intestinal damage in ulcerative colitis patients during clinical remission. Method: This is a cross-sectional study in which body composition data (phase angle [PhA] Lean mass was inversely correlated with non-specific inflammation marker (APMt vs. ESR) and directly correlated with hemoglobin values (MAMC vs. hemoglobin). Logistic regression analysis revealed that body cell mass was associated with disease extent (OR 0.92; 95CI 0.87-0.97; p<0.01). Conclusion: PhA was inversely correlated with inflammatory markers and directly correlated with lean mass. Acute inflammatory markers were correlated with disease extent. Body cell mass was associated with disease extent.

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“…According to available data, malnutrition affects 65-75% of patients with CD and 18-62% of patients with UC [34,35]. In pediatric IBD patients, malnutrition frequently results not only in weight loss but also in growth retardation [36,37].…”

Section: Nutritional Status Of Ibd Patientsmentioning

confidence: 99%

Nutritional Therapy for Inflammatory Bowel Disease

Orel¹,

Benedik²,

Eržen³

et al. 2018

New Concepts in Inflammatory Bowel Disease

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The components of a diet influence intestinal microbiota, epithelial barrier function, immune system, and many other factors that play important role in both development and treatment of inflammation in gastrointestinal tract. We briefly review potential role of specific dietary compounds as a risk or protective factor, but we predominantly concentrate on nutritional status and nutritional intervention in patients with inflammatory bowel disease. Besides exclusive enteral nutrition as a potential first-line treatment in active Crohn's disease, other nutritional therapeutic modalities such as partial enteral nutrition, parenteral nutrition, diets based on carbohydrate modifications, anti-inflammatory diet, and the use of specific dietary compounds with anti-inflammatory properties, known as pharmaconutrition, are presented.

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Micronutrient deficiencies in inflammatory bowel disease

Abstract: Micronutrient deficiencies are common and have clinical significance. High suspicion for micronutrient deficiencies is advocated so that treatable causes of morbidity are treated appropriately and late and irreversible sequlae are prevented.

Cited by 200 publications

References 50 publications

Dietary Habits and Nutrient Intake in Patients with Inflammatory Bowel Disease

Dietary Habits and Nutrient Intake in Patients with Inflammatory Bowel Disease

Associations among body composition, inflammatory profile and disease extent in ulcerative colitis patients

Nutritional Therapy for Inflammatory Bowel Disease

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