Micronutrient Imbalance

and, N. F. Suttle; Jones, Douglas

doi:10.1002/9780470753316.ch54

Cited by 16 publications

(78 citation statements)

References 35 publications

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“…The current paper will review recent research relating to the functionality of vitamin E and Se in relation to the ewe and her lambs with emphasis upon performance and immune function. The reader is referred to the following reviews to earlier work in this field (MacPherson 1994;Finch & Turner 1996;McDowell et al 1996;Suttle & Jones 2000).…”

Section: Introductionmentioning

confidence: 99%

Effects of vitamin E and selenium on the performance and immune status of ewes and lambs

Rooke

Robinson

Arthur³

2004

J. Agric. Sci.

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Inclusion in the diet of concentrations of vitamin E and selenium (Se) above requirement is associated with variable improvements in animal performance and immune function. At the cellular and molecular level, research in the last decade has produced a clearer understanding of the mechanisms underlying the multiple functions of vitamin E and Se and it is apparent that these functions extend beyond antioxidant protection. This paper reviews recent research relating to the functionality of vitamin E and Se in relation to the ewe and her lambs and attempts to relate this understanding to the whole animal level. Important aspects of this improved understanding are descriptions of three groups of seleno-proteins and the appreciation that there is a hierarchy in both the distribution of selenium between tissues and in the synthesis of different enzymes within tissues. In addition, there is diversity in the effects of vitamin E and Se derivatives on immune cell function. Given this heterogeneity in function it is not surprising that published responses for the production and health of ewes and lambs to supplementary vitamin E and selenium are variable and not always positive. Coupled with information on factors influencing variability in supply of vitamin E and Se from fresh and conserved forages and concentrate supplements, this review highlights the need for greater awareness of the importance of adequate supplementation of ewe and lamb diets with vitamin E and Se.

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Section: Introductionmentioning

confidence: 99%

Effects of vitamin E and selenium on the performance and immune status of ewes and lambs

Rooke

Robinson

Arthur³

2004

J. Agric. Sci.

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“…It is reported that a deficiency of minerals, such as calcium, phosphorus, sodium chloride, copper, zinc, manganese, cobalt, as well as vitamin or a protein deficiency might be the cause of the disease 1,2 . Only few reports are available on natural zinc deficiency in sheep in the literature due to the facts that pastures rarely contain less than 20 mg zinc kg -1 DM and that sheep are able to absorb zinc very efficiently at low intakes 3 . The young rapidly growing lambs achieve their high requirements for zinc from the ewes' milk which is rich in zinc (around 7 mg L -1 ) 4 .…”

Section: Introductionmentioning

confidence: 99%

Zinc Deficiency (Hypozincemia) in a Lamb: Clinical Field Case

Bida¹,

Garba²

2012

IJAVMS

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The purpose of this report was to present the clinical and pathological features of hypozincemia observed in a clinical field case and the effects of the administered treatment in the affected lamb. Zinc deficiency was diagnosed in a lamb flock of a four sheep; sucking lamb, dam, a ram and ewe in Minna, Nigeria. Skin lesions, anorexia, alopecia,depression, wool eating, flexed knees and a markedly stiff gait were observed in the lamb. The respiratory and heart rates were significantly higher (p<0.05) in zinc deficient lamb than in the apparently healthy ewes and ram in the flock.Pathology of skin of the zinc deficient lamb revealed mainlyparakeratosis accompanied by hyperkeratosis in the lesions. The animals responded rapidly to oral administration of zinc sulphate.This investigation revealed that zinc deficiency in lambs and probably other young sheep could result in wool eating and considerable economic losses because of damage to the quality of skin. We recommend that Zn, Fe and Cu be added to the diets of lambs to avoid wool eating. There is no documented report available on wool eating in sheep in this part of Nigeria and therefore suggest that research on biochemical and hematological analyses be conducted on flock of local sheep fed mainly leguminous diets to assess normal values and as well carry out surveillance of the syndrome for control.

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“…In ruminants, two clinical forms of the disease are recognised, congenital and delayed (Levander 1986;McDowell 2000). The former affects neonatal animals, which are stillborn or weak and usually die soon after birth, while the latter affects animals *3 weeks of age (McDowell 2000;Suttle and Jones 2000).…”

Section: Introductionmentioning

confidence: 99%