Microparticle sorting with a virtual optical chip

Abstract

We proposed an automatic sorting method based on a virtual optical chip, which was formed by a complex-amplitude beam shaping system. The automatic sorting of different micro-particles was realized by the optical forces of the intensity and phase gradients of the reconstructed optical beam. The method was verified with theoretical analysis and experimental results. Compared with the traditional optical sorting methods, the proposed one does not need high-precision mechanical and/or microfluidic devices. The optical chip is flexible in structure and efficient in optical sorting and can be used in the fields of medical detection and material sensing.

Intelligent Optimization Design of Automatic Sorting Robot Process

“…For example, ant optimization algorithm is inspired by the behavior of ants looking for the shortest distance between the nest and food. Particle swarm optimization algorithm simulates the flight of birds and the movement of searching for food, and artificial bee colony algorithm is inspired by the process of bees searching for food [7].…”

Non-Invasive Dynamic Reperfusion of Microvessels In Vivo Controlled by Optical Tweezers

“…In the reperfusion experiments at different positions, an effective redirection of RBCs was required. In microfluidic channels, the efficiencies of cell manipulation and sorting can be enhanced by moving the position of optical trap ( Wang et al, 2011 ; Landenberger et al, 2012 ; Zhou et al, 2021 ). Here, the suitable position of the optical trap should be obtained for redirection of RBCs in the microvessels in vivo .…”

Electromagnetic Forces and Torques: From Dielectrophoresis to Optical Tweezers

“…Copyright 2001 Wiley). (c) From top to bottom, the panel shows the use of SLMs for particle sorting (Adapted with permission from ref . Copyright 2021 AIP Publishing) and manipulation (Adapted with permission from ref .…”

“…Aside from separately using intensity and phase gradients for analyte transport, a number of works have also proposed their combined use in optical setups to achieve full control of single particles. ,− Here, as shown in Figure c, intensity gradients are used to confine the analyte along a predefined pattern while phase gradients are then employed to move the object inside it. This way, a synergy of intensity and phase forces is used to trap and transport particles and provide a higher degree of control over the trapped analyte.…”

“…This way, a synergy of intensity and phase forces is used to trap and transport particles and provide a higher degree of control over the trapped analyte. For example, as shown in Figure c, this configuration has allowed the sorting of microparticles by automatically directing particles of different sizes along different paths by exploiting their different interactions with phase gradient forces . We note that this combination of phase transport lines with intensity traps does not seem to have been proposed for DEP fields, but it would, in principle, be possible, for instance, by exploiting the different electrokinetic behaviors of cells as a function of the frequency of the applied DEP field …”