Microporous membrane formation via thermally-induced phase separation. II. Liquid—liquid phase separation

Lloyd, Douglas R.; Kim, Sung Soo; Kinzer, Kevin E.

doi:10.1016/0376-7388(91)80073-f

Cited by 456 publications

(172 citation statements)

References 8 publications

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“…Typically the membranes were left for 02 days to fully polymerize before use. The temperatures chosen are known to change the porosity of the membranes 24,25 . For the protein release study NRLb and NRLbBSA membranes were placed in 200 mL of aqueous solution, where the release behavior was observed.…”

Section: Methodsmentioning

confidence: 99%

Natural rubber latex used as drug delivery system in guided bone regeneration (GBR)

Herculano¹,

Silva²,

Ereno

et al. 2009

Mat. Res.

105

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In this work, we propose natural rubber latex (NRL) membranes as a protein delivery system. For this purpose Bovine Serum Albumin (BSA) was incorporated into the latex solution for in vitro protein delivery experiments. Different polymerization temperatures were used, from -10 to 27 °C, in order to control the membrane morphology. These membranes were characterized by Scanning Electron Microscopy (SEM), Atomic Force Microscopy (AFM), as well as the Lowry Method to measure the BSA release. SEM and AFM microscopy analysis showed that the number, size and distribution of pores in NRL membranes can be varied, as well as its overall morphology. We have found that the morphology of the membrane is the predominant factor for higher protein release, compared with pore size and number of pores. Results demonstrated that the best drug-delivery system was the membrane polymerized at RT (27 °C), which does release 66% of its BSA content for up to 18 days. Our results indicate that NRLb could be used in the future as an active membrane that could accelerate bone healing in GBR.

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Section: Methodsmentioning

confidence: 99%

Natural rubber latex used as drug delivery system in guided bone regeneration (GBR)

Herculano¹,

Silva²,

Ereno

et al. 2009

Mat. Res.

105

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“…The process yields relatively homogeneous, three-dimensional cellular structures with the cells interconnected by small pores [4]. Microporous polyolefin structures have been studied extensively for numerous reasons including the fact that they represent a low cost option [5][6][7].…”

Section: Introductionmentioning

confidence: 99%

Trapping citronellal in a microporous polyethylene matrix

Akhtar

Focke

2015

Thermochimica Acta

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The Flory-Huggins theory was used to model the phase behaviour of linear low density polyethylene-citronellal binary mixtures. The model parameters were obtained from fitting the bimodal phase envelope using data points from cloud point determinations. This allowed the prediction of the melting point depression curve as well as the location of the spinodal region. A microporous polyethylene matrix was obtained by quenching homogeneous liquid mixtures at temperatures well below the spinodal phase boundary. This strategy makes it possible to trap, and effectively solidify, large amounts of citronellal in a polyethylene (LLDPE) matrix. This has potential implications for the development of long-lasting insect repellent bracelets and anklets.

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“…During the last two decades, the preparation of porous membranes via thermally induced phase separation (TIPS) has received extensive attention because TIPS is a versatile and simple technique for producing porous polymer membranes (Castro, 1981;Soong 1985a, 1985b;Tsai and Torkelson, 1990;Lloyd et al, 1988Lloyd et al, , 1990Lloyd et al, , 1991Berghmans et al, 1996). Since TIPS membrane formation is a non-equilibrium process, the cooling rate significantly influences the resulting membrane structure.…”

Section: Introductionmentioning

confidence: 99%

Preparation of Microporous Polypropylene Membrane via Thermally Induced Phase Separation as Support of Liquid Membranes Used for Metal Ion Recovery.

Matsuyama

Teramoto

et al. 2003

J. Chem. Eng. Japan

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Microporous polypropylene (PP) membranes were prepared by the thermally induced phase separation (TIPS) technique and used as supports of liquid membranes. Several different quenching temperatures were used in the preparation of the microporous membranes. Membranes prepared by air-cooling and quenching in a water bath of 353 K showed higher porosity at the membrane surface compared with those made by quenching in a water bath of 303 K and in ice-water. A simplified one-dimensional heat transfer equation was solved to evaluate the temperature profile within the membrane to demonstrate the effect of quenching temperature on the final pore size distribution. The calculated result suggested that the asymmetric membrane structure formed by quenching in 303 K water and ice-water was not attributable to the temperature gradient.Supported liquid membranes (SLMs) were prepared by impregnating a carrier solution in the prepared porous polypropylene membranes, and uphill transport of Ce(III) was investigated using octyl(phenyl)-N,N-diisobutyl-carbamoyl-methylphosphine oxide (CMPO) as a carrier, tributyl phosphate (TBP) as a modifier, and dodecane as a solvent. The membranes prepared by air-cooling showed higher permeability of Ce(III) than the commercial membrane.

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Microporous membrane formation via thermally-induced phase separation. II. Liquid—liquid phase separation

Cited by 456 publications

References 8 publications

Natural rubber latex used as drug delivery system in guided bone regeneration (GBR)

Natural rubber latex used as drug delivery system in guided bone regeneration (GBR)

Trapping citronellal in a microporous polyethylene matrix

Preparation of Microporous Polypropylene Membrane via Thermally Induced Phase Separation as Support of Liquid Membranes Used for Metal Ion Recovery.

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