Micropulse diode laser trabeculoplasty – 180‐degree treatment

Rantala, Elina; Välimäki, Juha

doi:10.1111/j.1755-3768.2010.02026.x

Cited by 31 publications

(27 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In the present study, eyes with a lower number of medications did not have a better success rate than eyes with ≥ 3 medications. This observation was in agreement with our previous study on 180-degree MDLT treatment [16]. …”

Section: Discussionsupporting

confidence: 94%

The Outcome of 270-Degree Selective Laser Trabeculoplasty

Pehkonen

Välimäki

2012

Journal of Ophthalmology

View full text Add to dashboard Cite

Purpose. To evaluate the reduction of intraocular pressure (IOP) by a single-session 270° selective laser trabeculoplasty (SLT) in pseudoexfoliation glaucoma (PXFG) and primary open angle glaucoma (POAG) patients. Methods. A successful outcome was defined as an IOP reduction ≥20% from baseline with no further need for laser or incisional surgery. The preoperative pharmaceuticals were maintained unchanged throughout the course of the study. 70–80 nonoverlapping pulses were distributed around 270° in the trabecular band. Results. Sixty-six eyes of 42 patients with PXFG (30 eyes) or POAG (36 eyes) met the inclusion criteria. The mean ± standard deviation preoperative IOP was 23.7 ± 4.5 mmHg and at the end of the followup was 19.0 ± 4.5 mmHg with a pressure drop of 4.7 ± 3.1 mmHg (20%) (P < 0.001, 95% confidence interval 3.94–5.46). The cumulative probability of success was 39% (26 of 66 eyes) after 6 months of followup. Statistically significant differences in success rates were observed between the PXFG and POAG groups (27% versus 50%; P = 0.025). Postoperative inflammatory reaction was scanty. Conclusions. 270-degree SLT is useful in lowering IOP in PXFG and POAG, but the average reduction of IOP seems to be within the same range as reported with 180-degree SLT previously.

show abstract

Section: Discussionsupporting

confidence: 94%

The Outcome of 270-Degree Selective Laser Trabeculoplasty

Pehkonen

Välimäki

2012

Journal of Ophthalmology

View full text Add to dashboard Cite

show abstract

“…24 In our study, 73% of eyes that received 360° treatment achieved success with MLT. Our findings were consistent with Fea et al who reported using the 810 nm MLT that 75% of treated patients had an IOP reduction, with 60% of patients having >20% IOP reductions.…”

Section: Discussionmentioning

confidence: 48%

MicroPulse Laser Trabeculoplasty for the Treatment of Open-Angle Glaucoma

et al. 2015

View full text Add to dashboard Cite

The aim of the study was to investigate the safety and efficacy of using MLT in the treatment of open-angle glaucoma (OAG).This prospective cohort included subjects ≥18 years of age with OAG, defined as the open angle on gonioscopy with glaucomatous optic neuropathy evident from optical coherence tomography. Subjects with IOP < 21 mm Hg were classified as normal tension glaucoma and those with IOP ≥21 mm Hg were classified as primary open-angle glaucoma. Those with angle closure, secondary glaucoma, prior laser trabeculoplasty, use of systemic IOP-lowering medications, corneal pathologies, follow-up <6 months, recent intraocular surgery, or only 1 functional eye were excluded. A single session of unilateral MLT treatment was delivered using a 577 nm diode laser to 360° of the trabecular meshwork to reduce IOP or medication load. Medications were titrated up or down at 1 month after laser to achieve a 25% IOP reduction from presentation or an IOP <18 mm Hg, whichever was lower. The following were compared using the Repeated Measures ANOVA with Bonferroni's Multiple Comparison Test: IOP (on presentation, pre-MLT, day 1, 1 week, 1 month, 3 months, and 6 months after MLT) and the number of medications (pre-MLT, 3 months, and 6 months after MLT). After 6 months, responders with initial success to MLT (IOP reduction ≥20% at 1 month) received treatment in the fellow eye.In 48 subjects with OAG, the mean number of MLT shots applied was 120.5 ± 2.0 shots using a mean energy of 1000 mW per shot. Only 7.5% had a mild, self-limiting anterior uveitis postlaser with no change in the Snellen visual acuity at 6 months (P's > 0.5). The IOP and number of medications were significantly reduced at all time intervals following MLT compared to the pre-MLT level (P's < 0.0001). At 6 months, the IOP was reduced by 19.5% in addition to a 21.4% reduction in medication compared to pretreatment levels. The MLT success rate was 72.9%. During the first 6 months only 2.1% required a repeated laser trabeculoplasty.MLT was effective in reducing IOP and medications in OAG with minimal postlaser inflammation and low failure rate at 6 months following laser.

show abstract

“…The success rates for MLT were higher than some previously reported studies involved in achieving the goal of ≥3 mmHg IOP or ≥20.0% IOP reduction from baseline values, although one author utilized the 810 nm diode laser12 and the other only targeted the inferior meshwork 15. Our findings were also less efficacious than some reports, but had a smaller sample size11 and included shorter intervals of follow-up 16…”

Section: Discussionmentioning

confidence: 59%

“…In 2012, Rantala and Välimäki12 also studied 180° MLT treatment with the 810 nm diode laser, concluding that only 2.5% of patients experienced a ≥20.0% IOP decrease from baseline and 7.5% of patients had a ≥3 mmHg IOP decrease without further intervention. Conversely, Babalola13 utilized the 810 nm diode laser applied to the inferior 180° for MLT in a Nigerian population with a sustained IOP lowering effect from weeks to months with an average IOP decrease of 17.2%.…”

Section: Discussionmentioning

confidence: 99%

Selective laser trabeculoplasty vs micropulse laser trabeculoplasty in open-angle glaucoma

Abramowitz

Chadha

Kouchouk³

et al. 2018

OPTH

View full text Add to dashboard Cite

AimThe aim of this study was to prospectively compare the efficacy, safety, and tolerability of selective laser trabeculoplasty (SLT) vs micropulse laser trabeculoplasty (MLT) in reducing intraocular pressure (IOP) in open-angle glaucoma patients.Patients and methodsIn all, 38 patients were randomized to 360° MLT and 31 patients were randomized to 360° SLT. IOP was measured at intervals of 1 hour and 1, 1–6, 6–12, 6–24, 24–36, and 36–52 weeks. Patients completed a survey 1 week after the procedure. Patients with end-stage, neovascular, uveitic, or angle-closure glaucoma were excluded. Treatment response was defined as an IOP reduction of ≥20.0% or ≥3 mmHg from baseline.ResultsIOP was lowered to ≥3 mmHg from baseline among 37.0% of the micropulse patients and 36.0% of patients in the selective laser group at 24–52 weeks. Similarly, 29.6% of the micropulse patients and 36.0% of the selective laser patients experienced a 20.0% IOP decrease from baseline during the 24–52-week interval (P=0.77). Both groups revealed similar reductions in IOP as absolute values and percentage decreases from baseline at all intervals up to 52 weeks post treatment. There were more treatment failures in the micropulse group up to 52 weeks post laser treatment; however, this was not statistically significant. The micropulse group reported less pain both during and after the procedure (P=0.005).ConclusionMicropulse trabeculoplasty has demonstrated similar efficacy to SLT over a 52-week follow-up period with less discomfort experienced both during and after the procedure.

show abstract

Micropulse diode laser trabeculoplasty – 180‐degree treatment

Cited by 31 publications

References 9 publications

The Outcome of 270-Degree Selective Laser Trabeculoplasty

The Outcome of 270-Degree Selective Laser Trabeculoplasty

MicroPulse Laser Trabeculoplasty for the Treatment of Open-Angle Glaucoma

Selective laser trabeculoplasty vs micropulse laser trabeculoplasty in open-angle glaucoma

Contact Info

Product

Resources

About