2024
DOI: 10.1101/2024.01.26.577517
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MicroRNA-145 enhances lung cancer cell progression after exposure to lyophilized fertile hydatid cyst fluid ofEchinococcus granulosussensu stricto

Hosein Mosajakhah,
Dariush Shanehbandi,
Ehsan Ahmadpour
et al.

Abstract: There is increasing evidence that the secretory/excretory antigens of the larval stage of Echinococcus granulosus (hydatid cyst fluid; HCF) can induce both anticancer and oncogenesis effects between parasite-derived metabolites and various cancer lines. The dual role of miR-145 as a tumor suppressor or oncogene has been previously reported in cancers. Nevertheless, it remains unknown, how miR-145 induces apoptosis in HCF-treated lung cancer cells. The fertile HCF was obtained from sheep and subjected to purifi… Show more

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