2023
DOI: 10.3390/diseases11020077
|View full text |Cite
|
Sign up to set email alerts
|

MicroRNAs’ Role in Diagnosis and Treatment of Subarachnoid Hemorrhage

Abstract: Subarachnoid hemorrhage (SAH) is most commonly seen in patients over 55 years of age and often results in a loss of many productive years. SAH has a high mortality rate, and survivors often suffer from early and secondary brain injuries. Understanding the pathophysiology of the SAH is crucial in identifying potential therapeutic agents. One promising target for the diagnosis and prognosis of SAH is circulating microRNAs, which regulate gene expression and are involved in various physiological and pathological … Show more

Help me understand this report
View preprint versions

Search citation statements

Order By: Relevance

Paper Sections

Select...
1

Citation Types

0
1
0

Year Published

2024
2024
2024
2024

Publication Types

Select...
4

Relationship

0
4

Authors

Journals

citations
Cited by 4 publications
(1 citation statement)
references
References 78 publications
0
1
0
Order By: Relevance
“…45,46 Additionally, targeting specific microRNAs can affect the expression of intracellular metabolic enzymes. 47,48 These advancements enable molecular-level modulation of the metabolic activity of peripheral immune cells, potentially reversing the immune cascade reactions in peripheral blood. Thus, the development of drugs promoting the metabolic transition of T cells, B cells and monocytes in peripheral blood may prevent the occurrence and progression of aneurysms.…”
Section: Discussionmentioning
confidence: 99%
“…45,46 Additionally, targeting specific microRNAs can affect the expression of intracellular metabolic enzymes. 47,48 These advancements enable molecular-level modulation of the metabolic activity of peripheral immune cells, potentially reversing the immune cascade reactions in peripheral blood. Thus, the development of drugs promoting the metabolic transition of T cells, B cells and monocytes in peripheral blood may prevent the occurrence and progression of aneurysms.…”
Section: Discussionmentioning
confidence: 99%