Microscopic Polyangiitis (MPO-ANCA) and Henoch-Schoenlein purpura overlap in a Child

Abstract

MPO-ANCA and Henoch-Schoenlein purpura overlap are extremely rare in the pediatric population. We present a case with biopsy-proven IgA renal depositions and positive MPO in a 6-year-old child with the clinical presentation of vasculitis with cutaneous and renal involvement. The child was successfully treated with a combination of steroids and cyclophosphamide.