The alluvial environment of the Supía-Marmato mining district, in the Rio Medio Cauca region, Colombia, provided coarse and fine-grained gold that was used for prehispanic gold work and also fine-grained, gold-bearing sediments that were used for ceramic production. Three ceramic fragments, identified as Marrón Inciso-Quimbaya Clasico, were submitted for geochemical analysis in order to determine their elemental composition-the ICP (Inductively Coupled Plasma) data indicated: 2 -8 ppm Ag; 91 -367 ppm Au; 1 ppm Hg; 9 -73 ppm Pt; 10 -47 ppm Ni; 11 -60 ppm Pb; and one sample contained 34,800 ppm Cu. The Rio Medio Cauca is a broad north-south zone that runs from Cauca Dept., in the south, to Medellin, Antioquia Dept., in the north. This region also hosts numerous mineral occurrences and mines such as Marmato (Au-Ag) and La Colosa (Au-Cu). We conclude that this is the first study to define and establish a link between the metal content of prehispanic ceramics and Au, Ag, Cu, and Pt occurrences in Colombia.