Si-substituted biphasic calcium phosphates (Si-BCP) were prepared by co-precipitation method. X-ray diffraction and fourier transform infrared spectroscopy were used to characterize the structure of Si-BCP powders. The Si-BCP powders with various Ca/(P+Si) molar ratio were carried out on structural change of hydroxyapatite (HAp) and β-tricalcium phosphate (ß-TCP). The in-vitro bioactivity of the Si-BCP powders was determined by immersing the powders in SBF solution, after that observing the chemical composition and morphology change by X-ray diffraction, scanning electron microscope and energy dispersive spectroscopy.
Key words
서 론Calcium Phosphate계열의 일종인 수산화아파타이트 (hydroxyapatite, Ca 10 (PO 4 ) 6 (OH) 2 )는 생체내의 활성도가 뛰어나기 때문에 치과나 정형외과에서 치료목적으로 가 장 효율성이 뛰어난 생체세라믹스 재료로서 각광을 받았 으나, 최근 들어 수산화아파타이트의 뛰어난 생체활성도 와 더불어서 생분해성이 좋은 β-삼인산칼슘(tricalcium phosphate, β-Ca 3 (PO 4 ) 2 )을 결합한 이상(biphasic)의 calcium phosphate계열인 BCP(biphasic calcium phosphate) 의 연구가 활발히 진행되고 있다 [1][2][3][4][5][6]