In order to explore the active roll control of brake disc bolt load of heavy semi-trailer, the finite element simulation model of brake disc is constructed by using thermal coupling simulation algorithm, vehicle friction braking principle and heat transfer principle, and the temperature field and thermal stress bolt load of brake disc are analyzed. The results show that when analyzing the internal temperature of the brake disc, the heat transfers from the disc to the inner side, the temperature of the disc first rises and then decreases, and the internal temperature keeps rising. When analyzing the finite element model of the brake disc, it is found that during the braking process, the tensile stress and equivalent stress on the upper side of the bolt hole in the tooth of the brake disc are the largest parts, which are most vulnerable to damage. Therefore, through the research on active roll control of brake disc bolt load of heavy semi-trailer, the finite element simulation model is validated to meet the expectations. Although there are some shortcomings in the research process, it still provides some new ideas for the improvement of brake disc of heavy semi-trailer.