Microsurgical study of the interpeduncular cistern and its communication with adjoining cisterns

Sufianov, Albert; Sufianova, Galina Zinovievna; Iakimov, Iurii A.

doi:10.1007/s00381-008-0746-x

Cited by 16 publications

(6 citation statements)

References 13 publications

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“…The basal cisterns such as the interpeduncular fossa or the cisterns of the optic tract share some anatomical similarities with the conventional external subarachnoid spaces, in particular the existence of arachnoid membranes trabeculae. Yet, they display a more complex compartmentalization supported by the presence of several layers of the Liliequist’s membrane [19]. The more internal CSF-filled spaces include the velum interpositum pouches which are closely associated with the choroidal tissue, and the ambient cisterns which in rodents contain a large proportion of the intracranial fluid supply (Ghersi-Egea and Fenstermacher, unpublished data).…”

Section: Discussionmentioning

confidence: 99%

Brain leukocyte infiltration initiated by peripheral inflammation or experimental autoimmune encephalomyelitis occurs through pathways connected to the CSF-filled compartments of the forebrain and midbrain

Schmitt

Strazielle

Ghersi-Egea

2012

J Neuroinflammation

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BackgroundCerebrospinal fluid (CSF) has been considered as a preferential pathway of circulation for immune cells during neuroimmune surveillance. In order to evaluate the involvement of CSF-filled spaces in the pathogenesis of experimental autoimmune encephalomyelitis (EAE), a model of multiple sclerosis, we performed a time-course analysis of immune cell association with the CSF-containing ventricles, velae, and cisterns in two active models of this disease.MethodsGuinea-pig spinal cord homogenate-induced EAE in rat and myelin oligodendrocyte glycoprotein-induced EAE in mouse were used. Leukocyte distribution and phenotypes were investigated by immunohistochemistry in serial sections of brain areas of interest, as well as in CSF withdrawn from rat. Immune cells associated with the choroid plexuses were quantified.ResultsFreund’s adjuvant-induced peripheral inflammation in the absence of brain antigen led to a subtle but definite increase in the number of myeloid cells in the extraventricular CSF spaces. In both rats and mice, EAE was characterized by a sustained and initial infiltration of lymphocytes and monocytes within forebrain/midbrain fluid-filled compartments such as the velum interpositum and ambient cisterns, and certain basal cisterns. Leukocytes further infiltrated periventricular and pericisternal parenchymal areas, along perivascular spaces or following a downward CSF-to-tissue gradient. Cells quantified in CSF sampled from rats included lymphocytes and neutrophils. The distinctive pattern of cell distribution suggests that both the choroid plexus and the vessels lying in the velae and cisterns are gates for early leukocyte entry in the central nervous system. B-cell infiltration observed in the mouse model was restricted to CSF-filled extraventricular compartments.ConclusionThese results identified distinctive velae and cisterns of the forebrain and midbrain as preferential sites of immune cell homing following peripheral and early central inflammation and point to a role of CSF in directing brain invasion by immune cells during EAE.

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Section: Discussionmentioning

confidence: 99%

Brain leukocyte infiltration initiated by peripheral inflammation or experimental autoimmune encephalomyelitis occurs through pathways connected to the CSF-filled compartments of the forebrain and midbrain

Schmitt

Strazielle

Ghersi-Egea

2012

J Neuroinflammation

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“…They proposed that the Liliequist membrane, which is not fenestrated during ETV, may have blocked the flow of CSF from the third ventricle and lead to failure of the procedure (1). In the following years, the importance of Liliequist membrane perforation in the success of the ETV procedure was also noted by various authors (6,13,14).…”

Section: Etus V Et Al: Ultrastructural Changes In the Liliequist Memmentioning

confidence: 77%

“…In recent years, various reports have been published in the literature which focused on the microsurgical anatomy (10,14,18) and the radiological features of the Liliequist membrane (5).…”

Section: Etus V Et Al: Ultrastructural Changes In the Liliequist Memmentioning

confidence: 99%

“…Among these, the diencephalic leaf represents special interest for the endoscopic surgeon. The diencephalic leaf of the Liliequist membrane is attached to the infundibulum and pituitary stalk and to the mammillary bodies, is connected by thick arachnoid trabeculas to the bifurcation of the basilar artery, the precommunication part posterior cerebral arteries, with free edge of the diencephalic-mesencephalic leaf of Liliequist membrane which is in turn connected by arachnoid trabeculas to posterior communicating arteries, superior cerebellar arteries, the posterior perforated substance, and forms walls of the oculomotor cistern (14). The region of the subarachnoid space anterior and posterior to the diencephalic leaf can only communicate through the narrow space between the free superior margin of the diencephalic leaf, the optic tract, and the mesial surface of the temporal lobe, and through the gap around the PCoA in cases where it penetrates the diencephalic leaf (10).…”

Section: Etus V Et Al: Ultrastructural Changes In the Liliequist Memmentioning

confidence: 99%

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Ultrastructural changes in liliequist membrane in hydrocephalic process and its implications for endoscopic third ventriculostomy procedure

Etüş¹,

Solakoğlu²,

Ceylan³

2011

Turkish Neurosurgery

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AIm: Fenestration of Liliequist membrane (LM) during endoscopic third ventriculostomy (ETV) is extremely important for the success of the procedure. It is noteworthy that LM usually shows a tough and dense stucture in long-standing hydrocephalus cases different from its usual arachnoidal membrane-like structure observed in new-onset hydrocephalus cases. The structural variation of LM in different hydrocephalic states was investigated histologically in this study. mAterIAl and methOds: Specimens of LM obtained during endoscopic fenestration in 11 cases were examined under transmissionelectron-microscopy. Six cases had long-standing hydrocephalus and five had new-onset triventricular hydrocephalus. None of the cases had a history of infection or hemorrhage. results:In cases with long-standing hydrocephalus, ultrastructural examinations revealed the existence of regular and dense bundles of type-I collagen among the fibroblast-like cells, which were closely connected by dense desmosomes and gap-junctions. In cases with newonset hydrocephalus, it was observed that the cells usually had long cytoplasmic extentions and were connected with loose desmosomes. Sparse type-I collagen bundles were observed rarely among the cells. COnClusIOn:These results suggest that the structure of LM may change with the duration of the hydrocephalic process. This may help explain the tough and dense LM stucture observed during the ETV procedure in cases with long-standing-hydrocephalus.KeywOrds: Endoscopic third ventriculostomy, Hydrocephalus, Liliequist membrane, Transmission electron microscopy ÖZ AmAÇ: Endoskopik üçüncü ventrikülostomi (ETV) işleminde Liliequist membranının (LM) açılması, ETV başarısı açısından kritik öneme sahiptir. LM'nın özellikle uzun süreli hidrosefali olgularında, yeni gelişen hidrosefali olgularına kıyasla daha dirençli ve kalın yapıda oluşu dikkat çekicidir. Yazıda farklı hidrosefali süreçlerinde gözlenen bu yapısal farklılığın histolojik düzeyde incelenmesi amaçlanmıştır. yÖntem ve GereÇ: ETV uygulanan 11 olguda LM açılması sırasında elde edilmiş olan membran parçaları transmisyon elektron mikroskopisinde incelenmiştir. Olguların altı tanesinde "uzun süreli hidrosefali", beşinde ise "yeni başlangıçlı hidrosefali" sözkonusu olup, hiçbirinde geçirilmiş enfeksiyon veya kanama öyküsü yoktu.BulGulAr: Uzun süreçli hidrosefalinin sözkonusu olduğu olgulardan alınan dokularda fibroblast morfolojisi sergileyen hücrelerin arasında düzenli ve yoğun demetler halinde tip I kollajenin varlığı dikkat çekti. Kollajen demetleri arasındaki hücrelerin sık desmozomlar ve gap junctionlar aracılığıyla bağlantılı oldukları görüldü. Yeni başlangıçlı hidrosefali olgularına ait örneklerde ise hücrelerin uzun sitoplazmik uzantılara sahip oldukları ve seyrek desmozomlar aracılığıyla bağlantılı olmalarının yanısıra aralarında nadiren seyrek tip I kollajen lifleri bulunduğu dikkat çekti.sOnuÇ: Bu bulgular, LM'nın hidrosefalinin süresine bağlı olarak fibrozitesinin artması yönünde bir yapısal değişiklik içerisine girdiğini düşündürm...

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“…Various descriptions of the ambient cistern can be found in the literature, 1,3,[5][6][7][8]12,15,[16][17][18][19][20][21][22] and the anatomy of neurovascular structures in this region has been well il-lustrated. However, only few microscopic studies of the arachnoid membranes related to the ambient cistern have been published, 8,12,18 and in most studies the ambient cistern was considered to be a cistern extending across the tentorial incisura.…”

mentioning

confidence: 99%

Reinvestigation of the ambient cistern and its related arachnoid membranes: an anatomical study

Qi¹,

Fan²,

Zhang³

2011

JNS

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Microsurgical study of the interpeduncular cistern and its communication with adjoining cisterns

Abstract: The interpeduncular cistern is a compound bulk structure. This classification is necessary for the quantitative and qualitative study of the interpeduncular anatomy. Also, it is necessary to neurosurgeons for the guiding line in this region.

Cited by 16 publications

References 13 publications

Brain leukocyte infiltration initiated by peripheral inflammation or experimental autoimmune encephalomyelitis occurs through pathways connected to the CSF-filled compartments of the forebrain and midbrain

Brain leukocyte infiltration initiated by peripheral inflammation or experimental autoimmune encephalomyelitis occurs through pathways connected to the CSF-filled compartments of the forebrain and midbrain

Ultrastructural changes in liliequist membrane in hydrocephalic process and its implications for endoscopic third ventriculostomy procedure

Reinvestigation of the ambient cistern and its related arachnoid membranes: an anatomical study

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