Microvolt T-wave alternans in adults with complex congenital heart diseases

Trojnarska, Olga; Ciepłucha, Aleksandra; Bartczak, Agnieszka; Kramer, Lisa A.; Grajek, Stefan

doi:10.5603/cj.a2013.0124

Cited by 6 publications

(5 citation statements)

References 30 publications

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“…This included clinical signs and symptoms used to screen for PAH in other populations (eg, fatigue, dyspnea, palpitations and arrhythmia, volume retention, ECG changes), which are often noted in ACHD. 21 , 29 , 30 , 31 , 32 , 33 , 34 , 35 No clinically meaningful associations between patient characteristics and clinical course or rate of newly-diagnosed PAH were identified from ACHD-QuERI data. We are cautious not to overextend this conclusion, as valid quantification of newly diagnosed PAH requires hemodynamic assessment via RHC, which was performed in a minority of patients.…”

Section: Discussionmentioning

confidence: 99%

Timely PAH Identification in Adults With Repaired Congenital Heart Disease? The ACHD-QuERI Registry Insights

Landzberg,

Daniels,

Forfia

et al. 2023

JACC: Advances

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Section: Discussionmentioning

confidence: 99%

Timely PAH Identification in Adults With Repaired Congenital Heart Disease? The ACHD-QuERI Registry Insights

Landzberg,

Daniels,

Forfia

et al. 2023

JACC: Advances

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“…Sudden cardiac death (SCD) mostly resulting from ventricular arrhythmia remains a cause of mortality in 19-30% of adults with congenital heart defects [4]. Prime risk factors of MVA are summarized in Table 1.…”

Section: Discussionmentioning

confidence: 99%

Malignant Ventricular Arrhythmias After Surgery for Uncomplicated Congenital Atrial Septal Defect-Case Report

Liang

Guan

2020

Preprint

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Background:Malignant ventricular arrhythmias (MVA) occurring subsequent to a repair of uncomplicated congenital heart disease is scarcely described in literature.Case presentation:One adult patient following congenital atrial septal defect (ASD) repair underwent immediate postoperative refractory MAV and ventricular fibrillation. The recurrent episodes of shocks cannot be suppressed by drugs. Emergent re-exploration was performed and repeated closure of ASD and DeVega's annuloplasty were completed. The patient had uneventful recovery and no occurrence of arrhythmia.Conclusion: Malignant ventricular arrhythmias are rare and should never be overemphasized even during the repair of uncomplicated congenital heart defect. Re-exploration should be taken into consideration when MVA occurred in the early stage postoperatively.

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“…MTWA is an electrocardiographic (ECG) phenomenon displaying inhomogeneity of the myocardial repolarization process. The prognostic value of MTWA in ischemic heart diseases, heart failure, and cardiomyopathies has been demonstrated ( 16 - 19 ). Sakaki et al ( 20 ) reported that MTWA values higher than 65 microvolt were related with cardiac mortality in adult patients with left ventricular dysfunction.…”

Section: Discussionmentioning

confidence: 99%

Increased Microvolt T-wave Alternans in Children and Adolescents with Eisenmenger Syndrome

Karpuz

Hallioglu

Yılmaz³

2018

Anatol J Cardiol

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Objective:To determine the values of microvolt T-wave alternans (MTWA) in children and adolescents with Eisenmenger syndrome (ES) and controls.Methods:Thirteen were included in the study. After analyzing the 24-h ECG recordings, MTWA was considered using three leads (V5, V1, and aVF). Right heart catheterization and 6-minute walk test (6-MWD) were applied to the patients and pro-brain natriuretic peptide levels were assessed; echocardiographic parameters were obtained from both the groups and the results were compared.Results:The MTWA value in lead V5 was 81.08±10.73 µV in the patient group (63.50±18.78 µV in the control group), in lead V1 was 75.00±16.86 µV (73.94±16.77 µV in the control group), and in lead aVF was 73.77±17.81 µV (72.61±16.21 µV in the control group). Comparison of MTWA values between patients and controls revealed that only lead V5 values were statistically different in the ES group. The 6-MWD scores significantly correlated with lead V5. Right atrial volume and right ventricular fractional area change were significantly correlated with lead V1. The Tei index was significantly correlated with lead aVF.Conclusion:The MTWA lead V5 value was significantly higher in children with ES than in controls and was also correlated with decreased exercise tolerance.

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Microvolt T-wave alternans in adults with complex congenital heart diseases

Abstract: 1 ± 5.9 vs. 26.3 ± 6.7, p = 0.002),, p = 0.01). Multivariate logistic regression analysis proved that pulmonary hypertension (OR = 13.7, p = 0.03), male gender (OR = 10.4, p = 0.00002)

Cited by 6 publications

References 30 publications

Timely PAH Identification in Adults With Repaired Congenital Heart Disease? The ACHD-QuERI Registry Insights

Timely PAH Identification in Adults With Repaired Congenital Heart Disease? The ACHD-QuERI Registry Insights

Malignant Ventricular Arrhythmias After Surgery for Uncomplicated Congenital Atrial Septal Defect-Case Report

Increased Microvolt T-wave Alternans in Children and Adolescents with Eisenmenger Syndrome

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