Abstract:The 5-year recurrence-free (RFS) and overall survival (OS) rates in patients with ND-CLM (28.1% and 29.0%) were worse than those without ND-CLM (39.5% [p= 0.0079], 58.1% [p =0.0010]). In multivariate analysis, having ND-CLM was found to be an independent risk factor of impaired RFS (hazard ratio =1.81, p =0.0385) and OS (hazard ratio =2.06, p =0.0165 ). Conclusions: Detection of new lesions during hepatectomy negatively impacts on survival in patients undergoing surgery for colorectal liver metastases.
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