Microwave ablation is effective against liver metastases from gastric adenocarcinoma

Abstract

MWA is a safe and useful alternative for liver metastases from gastric adenocarcinoma in selected patients.

Long-term outcomes and prognostic analysis of percutaneous radiofrequency ablation in liver metastasis from breast cancer

“…In our study, the patients with 3-5 liver metastases had a median overall survival of 17 months, while those with 1-2 liver metastases had a median survival of 29 months (p ¼ .030). Zhou et al [40] published clinical results of microwave ablation in 32 patients with gastric adenocarcinoma liver metastasis and found that the number of liver metastases, therapeutic modalities and the presence of extrahepatic metastases were independent prognostic factors in a multivariate regression analysis. Multiple liver metastases were associated with poor biological behavior and treatment difficulty, ultimately influencing the patients overall survival [41].…”

Influence of thermal ablation of hepatic metastases from gastric adenocarcinoma on long-term survival

“…However, 7 of these articles were case reports and 9 of them were non-gastric related liver metastases. We finally selected 12 eligible articles [9–11,13–21] (Fig. 1).…”

“…Pooled analysis of 4 [13,14,19,21] studies included 190 patients: 88 in RFA/MWA group and 102 in systemic chemotherapy group (Fig. 2B).…”

“…2 studies were excluded: 1 [11] is about <2 cm versus >2 cm, the other [13] is about <4 cm versus >4 cm. Pooled analysis of 7 studies [9,10,14,16–18,21] included 182 patients receiving thermal ablation. This pooled analysis demonstrated that size of hepatic metastases less than 3 cm was associated with a significantly improved survival compared with larger 1 (HR = 1.46; 95% CI 1.03–1.88; P = .002) (Fig.…”

Comparative Study of Drug-eluting Beads versus Conventional Transarterial Chemoembolization for Treating Peculiar Anatomical Sites of Gastric Cancer Liver Metastasis

“…The main therapeutic methods are surgical resection, systemic chemotherapy, molecular targeted therapy, immunotherapy, and interventional therapy [ 1 , 14 , 16 ]. Simultaneous and heterogeneous liver metastases of gastric cancer can be treated by surgical resection or ablation, and both can respond to treatment [ 17 , 18 ]. There are some difficulties involved in the surgical treatment and ablation of multiple lesions and metastasis of special anatomical sites.…”