Microwave Ablation of Renal Cell Carcinoma of the Transplanted Kidney: Two Cases

Favi, Evaldo; Raiteri, M.; Paone, G.; Alfieri, Carlo; Ferraresso, Mariano

doi:10.1007/s00270-019-02302-w

Cited by 4 publications

(1 citation statement)

References 21 publications

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“…The procedures were performed under CT-guidance via a percutaneous or a trans-osseous approach with no serious complications, no allograft dysfunction, and no recurrence after a follow-up ranging from 8 to 61 mo. Other two cases of MWA of RCC of the transplanted kidney were more recently described by our group[ 69 ]. More in details, we treated one Fuhrman grade 2, T1aN0M0 papillary RCC and one Fuhrman grade 1, T1aN0M0 clear cell RCC.…”

Section: Treatment Options and Treatment-specific Outcomesmentioning

confidence: 95%

Treatment options for localised renal cell carcinoma of the transplanted kidney

Motta¹,

Ferraresso²,

Lamperti³

et al. 2020

WJT

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Currently, there is no consensus among the transplant community about the treatment of renal cell carcinoma (RCC) of the transplanted kidney. Until recently, graftectomy was universally considered the golden standard, regardless of the characteristics of the neoplasm. Due to the encouraging results observed in native kidneys, conservative options such as nephron-sparing surgery (NSS) (enucleation and partial nephrectomy) and ablative therapy (radiofrequency ablation, cryoablation, microwave ablation, high-intensity focused ultrasound, and irreversible electroporation) have been progressively used in carefully selected recipients with early-stage allograft RCC. Available reports show excellent patient survival, optimal oncological outcome, and preserved renal function with acceptable complication rates. Nevertheless, the rarity and the heterogeneity of the disease, the number of options available, and the lack of long-term follow-up data do not allow to adequately define treatment-specific advantages and limitations. The role of active surveillance and immunosuppression management remain also debated. In order to offer a better insight into this difficult topic and to help clinicians choose the best therapy for their patients, we performed and extensive review of the literature. We focused on epidemiology, clinical presentation, diagnostic work up, staging strategies, tumour characteristics, treatment modalities, and follow-up protocols. Our research confirms that both NSS and focal ablation represent a valuable alternative to graftectomy for kidney transplant recipients with American Joint Committee on Cancer stage T1aN0M0 RCC. Data on T1bN0M0 lesions are scarce but suggest extra caution. Properly designed multi-centre prospective clinical trials are warranted.

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Section: Treatment Options and Treatment-specific Outcomesmentioning

confidence: 95%

Treatment options for localised renal cell carcinoma of the transplanted kidney

Motta¹,

Ferraresso²,

Lamperti³

et al. 2020

WJT

Self Cite

View full text Add to dashboard Cite

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A review of antenna designs for percutaneous microwave ablation

et al. 2021

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Microwave (MW) antenna is a key element in microwave ablation (MWA) treatments as the means that energy is delivered in a focused manner to the tumor and its surrounding area. The energy delivered results in a rise in temperature to a lethal level, resulting in cell death in the ablation zone. The delivery of energy and hence the success of MWA is closely dependent on the structure of the antennas. Therefore, three design criteria, such as expected ablation zone pattern, efficiency of energy delivery, and minimization of the diameter of the antennas have been the focus along the evolution of the MW antenna. To further improve the performance of MWA in the treatment of various tumors through inventing novel antennas, this article reviews the state-of-the-art and summarizes the development of MW antenna designs regarding the three design criteria.

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