Microwave‐assisted aqueous synthesis of new quaternary‐alloyed CdSeTeS quantum dots; and their bioapplications in targeted imaging of cancer cells

Yang, Fengzhao; Xu, Zhancheng; Wang, Jinjie; Zhang, Feng; Dong, Chaoqing; Ren, Jicun

doi:10.1002/bio.2395

Cited by 23 publications

(20 citation statements)

References 56 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…CdTeSe cores were prepared following amodified method described in [9][10][11][12][13][14]. Core-shell alloy quantum dots were prepared according to a modified SILAR protocol that has been previously published [13].…”

Section: Synthesis Methodsmentioning

confidence: 99%

Synthesis, Structural and Optical Characterization of CdTeSe/ZnSe and CdTeSe/ZnTe Core/Shell Ternary Quantum Dots for Potential Application in Solar Cells

Hưng

Thang

Nong

et al. 2016

Journal of Elec Materi

View full text Add to dashboard Cite

International audienceThis work presents the results on the fabrication, structural and optical properties of CdTeSe/ZnTe and CdTeSe/ZnSe n monolayers (ML) (with n = 0,1,2,4 and 6 being the nominal shell monolayer thickness) ternary alloyed core/shell quantum dots (QDs). Transmission electron microscopy has been used to observe the shape and size of the QDs. These QDs crystallize at the zinc-blende phase. Raman scattering has been used to characterize the CdTeSe QDs’ alloy composition in the fabrication and coating processes. The Raman spectrum of CdTeSe QDs, in the frequency range from 100 cm−1 to 300 cm−1, is a composite band with two peaks at 160 cm−1 and 192 cm−1. When the thickness of the ZnTe shell is 4 ML, the peak of the Raman spectrum only appears at 160 cm−1. For the ZnSe 4 ML shell, the peak only appears at ∼200 cm−1. This shows that the nature of the CdTeSe QDs is either CdTe-rich or CdSe-rich depending on the shell of each sample. The shell thickness of 2 ML does not change the ternary core QDs’ crystalline phase. The absorption and photoluminescence spectra show that the absorption and emission bands can be shifted to 900 nm, depending on each ternary alloyed QD core/shell sample. This near-infrared spectrum region is suitable␣for applications in solar cells

show abstract

Section: Synthesis Methodsmentioning

confidence: 99%

Synthesis, Structural and Optical Characterization of CdTeSe/ZnSe and CdTeSe/ZnTe Core/Shell Ternary Quantum Dots for Potential Application in Solar Cells

Hưng

Thang

Nong

et al. 2016

Journal of Elec Materi

View full text Add to dashboard Cite

show abstract

“…The strong fluorescent stability of QDs also shows superiority in research on living animal. In recent years, Ren et al have reported CdSeTeS QDs modified with alpha-thioomega-carboxy poly(ethylene glycol) (HS-PEG-COOH), and the modified QDs were linked to anti-epidermal growth factor receptor (EGFR) antibodies [62]. QDs with the EGFR antibodies as labeling probes were successfully applied to targeted imaging for EGFR on the surface of SiHa cervical cancer cells through conjugation of QDs with the anti-EGFR antibodies.…”

Section: The Applications Of Quantum Dots In Tumor Diagnosticmentioning

confidence: 99%

Application of functional quantum dot nanoparticles as fluorescence probes in cell labeling and tumor diagnostic imaging

Zhao¹,

Zeng²

2016

Nano Online

View full text Add to dashboard Cite

Quantum dots (QDs) are a class of nanomaterials with good optical properties. Compared with organic dyes, QDs have unique photophysical properties: size-tunable light emission, improved signal brightness, resistance against photobleaching, and simultaneous excitation of multiple fluorescence colors. Possessing versatile surface chemistry and superior optical features, QDs are useful in a variety of in vitro and in vivo applications. When linked with targeting biomolecules, QDs can be used to target cell biomarkers because of high luminescence and stability. So QDs have the potential to become a novel class of fluorescent probes. This review outlines the basic properties of QDs, cell fluorescence labeling, and tumor diagnosis imaging and discusses the future directions of QD-focused bionanotechnology research in the life sciences.Keywords: Nanoparticles; Quantum dots; Optical properties; Biomaterials ReviewQuantum dots (QDs) are a kind of semiconductor fluorescent semiconductors, which have gained attraction in recent years by scientists as a novel fluorescent probe [1][2][3][4][5][6]. Compared with conventional organic fluorescent probes, QDs have shown great potential to be fluorescent probes and images in biology because of their unique optical properties [7][8][9][10][11][12][13][14][15]. Alivisatos and Nie employed QDs as fluorescent probes in biological staining and diagnostics that provided a novel study to display QDs as labels for cell and tissue research [16,17]. In recent years, QDs have been widely used in many fields of life sciences as fluorescent markers [18][19][20][21]. Herein, we briefly review the basic properties of QDs and the application of functionalized QDs as fluorescent probes in biological systems. The unique properties of quantum dotsQDs have unique optical and electrical properties due to its quantum effect and size effect. When the size of a particle is of nanometer scale, it will cause quantum confinement effect, size effect, dielectric confinement effect, macroscopic quantum effect, and surface effect. Consequently, QDs exhibit many optical properties different from macroscopic materials, and they have a very broad application prospects in biological fluorescent probes and functional materials. Therefore, QDs will have a meaningful effect on the continued development of life sciences [22][23][24][25][26][27][28]. Quantum dots have unique optical propertiesQDs have gained attraction owing to their unique fluorescence properties, which are due to the electron-hole and the interaction with the surrounding environment. When the excitation level of photon exceeds the band gap, the QDs will absorb photons to make the electrons transit from the valence band to the conduction band and shine. And if the composition and size of the QDs changed, they could obtain the emission spectra within the range from blue to red [29][30][31]. Conversely, when we want to obtain a variety of colors from multifarious fluorescent dyes, we often need a variety of excitation light, which not only incre...

show abstract

“…The unprecedented research boom that has occurred over the past two decades with respect to the chemistry of semiconductor nanocrystal quantum dots (QDs) stems from their intriguing electronic and optical properties such as their high surface-tovolume-ratio, size-tunable photoluminescence (PL) spectra, narrow emission and broad absorption spectra, bright fluorescence and high resistance to photo-initiated degradation and CdSeTeS [24]. To the best of our knowledge, the synthesis of alloyed quaternary CdSeTeS core QDs, which is of interest in this work, have only been reported once in literature and they were synthesized via a microwave assisted aqueous method [24].…”

Section: Introductionmentioning

confidence: 99%

“…To the best of our knowledge, the synthesis of alloyed quaternary CdSeTeS core QDs, which is of interest in this work, have only been reported once in literature and they were synthesized via a microwave assisted aqueous method [24].…”

Section: Introductionmentioning

confidence: 99%

Structural and optical properties of alloyed quaternary CdSeTeS core and CdSeTeS/ZnS core–shell quantum dots

Adegoke

Nyokong

Forbes

2015

Journal of Alloys and Compounds

View full text Add to dashboard Cite

Synthesis of fluorescent alloyed quantum dots (QDs) with unique optical properties suitable for a wide array of chemical, physical and biological applications is of research interest. In this work, highly luminescent and photostable alloyed quaternary CdSeTeS core QDs of two different sizes were fabricated via the organometallic hot-injection synthetic route. Characterization of the nanocrystals were performed using TEM, XRD, UV/vis and fluorescence spectrophotometric techniques. We have demonstrated in this work that the well fabricated alloyed quaternary CdSeTeS core QDs possess unique optical properties that are advantageous over conventional core/shell systems. Formation of the CdSeTeS/ZnS core/shell with the desired optical properties comes with a number of challenges, hence the advantages of the quaternary alloyed core over the core/shell QDs are (i) avoidance of the challenging process of determining the proper shell thickness which can provide the desired optical properties in the core/shell system and (ii) avoidance of the lattice-induced mismatch between the core and the shell material which can either lead to incomplete exciton confinement or dislocation at the core/shell interface.

show abstract

Microwave‐assisted aqueous synthesis of new quaternary‐alloyed CdSeTeS quantum dots; and their bioapplications in targeted imaging of cancer cells

Cited by 23 publications

References 56 publications

Synthesis, Structural and Optical Characterization of CdTeSe/ZnSe and CdTeSe/ZnTe Core/Shell Ternary Quantum Dots for Potential Application in Solar Cells

Synthesis, Structural and Optical Characterization of CdTeSe/ZnSe and CdTeSe/ZnTe Core/Shell Ternary Quantum Dots for Potential Application in Solar Cells

Application of functional quantum dot nanoparticles as fluorescence probes in cell labeling and tumor diagnostic imaging

Structural and optical properties of alloyed quaternary CdSeTeS core and CdSeTeS/ZnS core–shell quantum dots

Contact Info

Product

Resources

About