Microwave-assisted rapid synthesis, characterization and application of poly (d,l-lactide)-graft-pullulan

Tang, Xiaojiao; Huang, Jun; Xu, Liangyu; Song, Juan; Yang, Li; Yuan, Dan; Wu, Hailing

doi:10.1016/j.carbpol.2014.02.038

Cited by 13 publications

(8 citation statements)

References 33 publications

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“…1) were attributed to internal and terminal methine protons of PLA, respectively [7,9,11,61]. terminal groups indicates that the PLA chain is grafted onto the CG structure [11] and the absence of a signal at 1.66 ppm, characteristic of the lactide monomer [12], suggests the absence of residual monomer in the purified copolymers.…”

Section: Nmr Spectroscopymentioning

confidence: 99%

“…The particle size value of this Pickering emulsion was closer to that obtained by self-assembling (241 ± 5 nm). Graft copolymer of PLA with other polysaccharide such chitosan [18], pullulan [11,12], and chondroitin sulfate [61] have been synthesized and characterized by DLS.…”

Section: Particle Sizementioning

confidence: 99%

“…Poly (lactic acid) (PLA) is biocompatible, bio-absorbable and biodegradable and it has been approved by the US Food and Drug Administration (FDA) as a biomaterial [5,6]. Copolymers of PLA and polysaccharides, such as cellulose, starch, chitosan and pullulan have been reported [7][8][9][10][11][12][13][14][15][16]. Recent studies have addressed synthesis methods and applications as well as the development of potential delivery systems for hydrophobic drugs, due to the capacity to form amphiphilic micelles through self-organization [7][8][9][10][11][12][13][14][15][16].…”

Section: Introductionmentioning

confidence: 99%

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Self-assembling cashew gum-graft-polylactide copolymer nanoparticles as a potential amphotericin B delivery matrix

Richter¹,

Carneiro²,

Sousa³

et al. 2020

International Journal of Biological Macromolecules

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Section: Nmr Spectroscopymentioning

confidence: 99%

Section: Particle Sizementioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Self-assembling cashew gum-graft-polylactide copolymer nanoparticles as a potential amphotericin B delivery matrix

Richter¹,

Carneiro²,

Sousa³

et al. 2020

International Journal of Biological Macromolecules

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“…The process of water removal and the subsequent lactic acid polycondensation under microwave irradiation takes place 10-15 times faster than at conventional thermal heating [18,28,29]. Direct LA condensation is carried out in three stages, namely, removal of free water, polycondensation of oligomers and condensation of high molecular weight polymers in the melt.…”

Section: Introductionmentioning

confidence: 99%

Dehydration/polycondensation of lactic acid under microwave irradiation

Guba¹,

Gusar²,

Bakibayev³

et al. 2019

Bull. of the Kar. Univ. "Chem". Ser.

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Dehydration/polycondensation of lactic acid under microwave irradiation In this paper the effect of microwave irradiation power (MW) on the processes of polycondensation of lactic disturbed total internal reflection acid (LA) was studied for the first time. LA polycondensation was carried out in a multimodal reactor in a vacuum while bubbling with nitrogen at powers of 80, 130, 280, 360 and 500 watts. The change in the temperature of the LA sample under conditions of MW as a function of time and irradiation power was determined. Based on the data of 1H NMR and IR spectroscopy, it was suggested that at 80 W the molecules of physically bound water are mainly removed. The formation of lactic acid oligomers (LAO) occurs at a power of 130-280 W along with the removal of water and LA. Complete removal of water from LAO occurs at 360 watts. When LA is heated at MW power of 430 W, the formation and isolation of colorless crystals is observed, which can be classified by the IR spectra as lactide molecules (νC=O is 1770 cm-1 , νC-O-C is 1240 cm-1). The molecular weight of LAO decreases at a power of 430 W and above. The kinetic curves of LA polycondensation at 130, 280 and 360 W are presented. The process of LA polycondensation at 360 watts is optimal. It was established that the rate of LA dehydration under MW conditions increases by 15-20 times as compared with carrying out the process under normal heating conditions.

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“…Exfoliation takes place when the decomposition rate of the oxygen functional groups of GO exceeds the diffusion rate of the evolved gases, thus yielding pressures that exceed the Van der Waals forces that hold the graphene sheets together [47]. Microwaves, as an alternative energy input source, have been widely used not only for the expansion of GO but also in the field of organic synthesis [48][49][50], environmental remediation [51][52][53], preparation of catalysts [54][55][56] and activated carbon [57][58][59]. Carbon materials and particularly graphene-based materials have attracted intense interest as electrode materials for electrochemical capacitors due to their high surface area, electrical conductivity, chemical stability and low cost.…”

Section: Introductionmentioning

confidence: 99%