Microwave-Assisted Rapid Synthesis of Luminescent Tryptophan-Stabilized Silver Nanoclusters for Ultra-Sensitive Detection of Fe(III), and Their Application in a Test Strip

Abstract

A new preparation method for extreme fluorescent green emission tryptophan-stabilized silver nanoclusters (Tryp-AgNCs) is presented in this scientific research. The produced silver nanoclusters are dependent on tryptophan amino acid which contributes to normal growth in infants and the sublimation and recovery of human protein, muscles, and enzymes. Herein, we have introduced a green method by using microwave-assisted rapid synthesis. The subsequent silver nanoclusters (AgNCs) have excitation/emission peaks at 408/498 nm and display a considerable selectivity to Fe(III) ions. The tryptophan amino acid molecule was used in the synthesis process as a reducing and stabilizing agent. The Tryp-AgNCs’ properties were investigated in terms of morphology, dispersity, and modification of the synthesized particles using different advanced instruments. The luminescent nanoclusters traced the Fe(III) ions by the luminescence-quenching mechanism of the Tryp-AgNCs luminescence. Therefore, the extreme selectivity of the prepared nanoclusters was exhibited to the Fe(III) ions, permitting the sensitive tracing of ferric ions in the lab and in the real environmental samples. The limit of detection for Fe(III) ions based on Tryp-AgNCs was calculated to be 16.99 nM. The Tryp-AgNCs can be efficiently applied to a paper test strip method. The synthesized nanoclusters were used efficiently to detect the Fe(III) ions in the environmental samples. Moreover, we examined the reactivity of Tryp-AgNCs on various human tumor cell lines. The results show that the Tryp-AgNCs exhibited their activity versus the cancer cells in a dose-dependent routine for the perceived performance versus the greatest-used cancer cell lines.

Low-Cost Antenna-Array-Based Metamaterials for Non-Invasive Early-Stage Breast Tumor Detection in the Human Body

“…Figure 20 shows the surface current distribution for the proposed antenna-loaded artificial magnetic conductor. As we can see from the figure below, the surface current flows from the two microstrips and distribution for both sides also flows in a parallel and anti-parallel direction around the circular patch, in agreement with other methods [ 44 ].…”

A Reversible Optical Sensor Film for Mercury Ions Discrimination Based on Isoxazolidine Derivative and Exhibiting pH Sensing

“…Moreover, the recycling of the sensing affinity based on the binding of the IXZD-Hg(II) complex was investigated by the titration of the IXZD film versus ethylenediaminetetraacetic acid (EDTA) in the presence of Hg(II) [ 45 , 46 , 47 ]. Introducing EDTA to the surrounding medium with the sensor film after adding the Hg(II) ions increases the emission peak at 399 nm and subsequently decreases the 481 nm peak.…”

Rapid Detection of Ag (I) via Size Induced Photoluminescence Quenching of Biocompatible Green Emitting L-Tryptophan Scaffolded Copper Nanocluster

“…Owing to its high reduction potential, Ag(I) can be easily converted to Ag(0) in the presence of any mild reducing agent. Previously small molecules like tryptophan have been assigned as a reducing agent for the reduction of the metal core during the formation of a stable nanocluster [21,62]. Thus adding Ag(I) to the Trp-Cu NC can undergo a metallophilic interaction with the Cu core followed by a rapid reduction to Ag(0) by tryptophan and hydrazine present in the system.…”

“…In protein capped metal nanoclusters, small amino acids like tryptophan and tyrosine play a crucial role in protecting the nanocluster by coordinating with the metal core as well as reducing the metal ions [18][19][20][21]. Thus one might anticipate that the individual amino acids can also play a similar role outside the protein structure forming a stable ultrasmall nanocluster without the involvement of a large macromolecule, where the surface properties can be easily tuned.…”