Microwave-assisted synthesis of 11-substituted-3,3-dimethyl-2,3,4,5,10,11-hexahydrodibenzo[b,e][1,4]diazepin-1-one derivatives catalysed by silica supported fluoroboric acid as potent antioxidant and anxiolytic agents

Immobilized nickel boride nanoparticles on magnetic functionalized multi-walled carbon nanotubes: a new nanocomposite for the efficient one-pot synthesis of 1,4-benzodiazepines

“…In recent years, extensive investigations have been devoted to exploring the applicability of one-pot multicomponent reactions (MCRs) in the development of facile, straightforward, and highly efficient methodologies for the synthesis of a broad range of 1,4-benzodiazepines. 18 Among them, a number of catalytic systems and methodologies for the synthesis of 1,4-benzodiazepines based on the condensation of o -phenylenediamine with dimedone and various aldehydes, each of which holds a unique position in the synthesis of heterocyclic compounds, have been reported by researchers, such as UiO-66 MOF, 31 La 2 O 3 /La(OH) 3 , 33 GO nanosheets, 34 Gr@TiO 2 NCs, 35 Cu( ii )/PI-COF, 36 acetic acid/water under microwave irradiation, 37 sulfated polyborate, 38 B(HSO 4 ) 3 , 39 l -proline, 40 CuFe 2 O 4 , 41 Fe(OTs) 3 /SiO 2 , 42 CoFe 2 O 4 @GO-K22, 43 CoFe 2 O 4 @SiO 2 @NH-NH 2 -PCuW, 44 CeO 2 /CuO@GQDs@NH 2 , 45 [H-PFBA][PF 6 ], 46 [H-NMP][HSO 4 ], 47 ZnS nanoparticles, 48 Fe 3 O 4 @chitosan, 49 Fe( iii )-NicTC@nSiO 2 , 50 SrFe 12 O 19 , 51 chitosan functionalized by triacid imide, 52 HBF 4 –SiO 2 , 53 SPINOL-derived chiral phosphoric acid, 54 and oxalic acid. 55 Although each of these methods has its own advantages, they also have several shortcomings that need to be addressed.…”