2019
DOI: 10.2174/1385272823666190213114104
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Microwave-Assisted Synthesis of Bile Acids Derivatives: An Overview

Abstract: : The first attempts at microwave-assisted (MW) syntheses of bile acid derivatives were performed in domestic MW appliances. However, the reproducibility of these syntheses, which were performed in uncontrolled conditions, was very low. In the first part of this overview, compounds synthesized under such conditions are presented. Consequently, with the development of MW technology, MW-assisted reactions in MW reactors became reproducible. Thus, in the second part of this review, syntheses of bile acidsbased co… Show more

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Cited by 4 publications
(1 citation statement)
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“…Recently many laboratories, including our own, have described microwave-assisted reactions of bile acids. 15,[18][19][20] Synthesis of bile acid derivatives proceeded in a highly-accelerated manner and the yields and purity of the final products were excellent. These results encouraged us to move forward in the synthesis of potentially biologically active bile acid esters with a slightly longer carbon chain, in contrast to common bile acid esters.…”
Section: Introductionmentioning
confidence: 99%
“…Recently many laboratories, including our own, have described microwave-assisted reactions of bile acids. 15,[18][19][20] Synthesis of bile acid derivatives proceeded in a highly-accelerated manner and the yields and purity of the final products were excellent. These results encouraged us to move forward in the synthesis of potentially biologically active bile acid esters with a slightly longer carbon chain, in contrast to common bile acid esters.…”
Section: Introductionmentioning
confidence: 99%