Microwave-assisted synthesis of functionalized carbazoles via palladium-catalyzed aryl C–H activation and study of their interactions with calf-thymus DNA

Update on novel synthetic approaches towards the construction of carbazole nuclei: a review

“…in DMF and alteration with microwave irradiation for the synthesis of substituted carbazoles 55b in 20–95% yields. 72 The Pd-catalyzed strategy was also amenable for the synthesis of 1-hydroxy carbazoles under aerobic conditions ( Scheme 14 ). The plausible mechanism proposed for the synthesis of carbazoles 55a and 55b took place in four steps which involved the synthesis of pallado σ-complex A by in situ generated Pd(0) species via oxidative addition.…”

“…Mechanistic details for the synthesis of carbazoles 55a and 55b. 71,72 Scheme 16 Pd-catalyzed C-H amidation for synthesis of 1-hydroxy carbazoles.…”