Midbrain atrophy in subcortical ischemic vascular dementia

Sung, Young-Hee; Park, Ki-Hyung; Lee, Yeung-Bae; Park, Hyeon-Mi; Shin, Dong Jin; Park, Jea-Sul; Oh, Mi‐Sun; Ma, Hyeo-Il; Yu, Kyung‐Ho; Kang, Suk-Yun; Kim, Yun Joong; Lee, Byung‐Chul

doi:10.1007/s00415-009-5226-z

Cited by 19 publications

(20 citation statements)

References 36 publications

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“…21 On the fluid-attenuated inversion recovery (Flair) axial image, bicaudate ratio, defined as the minimum intercaudate distance divided by brain width along the same line, was measured where the heads of the caudate nuclei were most visible and closest to one another. 22 On the same image third ventricular width was measured via a line drawn through the long axis of the third ventricle, parallel to the interhemispheric fissure where the third ventricle was most visible.…”

Section: Image Analysismentioning

confidence: 99%

Late-onset multiple sclerosis presenting with cognitive dysfunction and severe cortical/infratentorial atrophy

et al. 2014

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Section: Image Analysismentioning

confidence: 99%

Late-onset multiple sclerosis presenting with cognitive dysfunction and severe cortical/infratentorial atrophy

et al. 2014

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“…The length of the M TEGM was measured on an axial T1-weighted image using the method of Sung et al [14]. Using a midmammillary-body image, the distance between the anterior interpeduncular fossa to the center of the cerebral aqueduct was measured [14,15]. The MGS was measured on axial T2-weighted images using the method of Adachi et al [16].…”

Section: Methodsmentioning

confidence: 99%

“…M = Midbrain area; P = pons area. b The length of the M TEGM was measured on an axial T1-weighted image using the method of Sung et al [14]. c , d MGS was measured on an axial T2-weighted image at the mammillary body level using the method of Adachi et al [16].…”

Section: Methodsmentioning

confidence: 99%

“…The pons included the area between the lines along the anterior and posterior margins of the pons and lines 1 and 2 [10,11,12,13]. The length of the M TEGM was measured on an axial T1-weighted image using the method of Sung et al [14]. Using a midmammillary-body image, the distance between the anterior interpeduncular fossa to the center of the cerebral aqueduct was measured [14,15].…”

Section: Methodsmentioning

confidence: 99%

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Differential Progression of Midbrain Atrophy in Parkinsonism: Longitudinal MRI Study

Hwang

Yang²,

Kim³

et al. 2016

Neurodegener Dis

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Aims: To elucidate different patterns of progression of midbrain atrophy in patients with Richardson's syndrome (RS), progressive supranuclear palsy-parkinsonism (PSP-P), and Parkinson's disease (PD) using magnetic resonance imaging (MRI)-based visual rating indexes. Methods: We recruited 12 patients with PSP-RS, 12 with PSP-P, and 23 with PD for whom MRIs had been followed up for at least 2 years (mean ± SD, 4.9 ± 1.6 years) after the initial MRI. MRI-based visual rating indexes were used to estimate midbrain atrophy, including the ratio of the pontine to midbrain tegmental areas (P/M ratio) on a midsagittal image, the length between the interpeduncular fossa and the center of the cerebral aqueduct at the midmammillary-body level (M^TEGM) on axial images, and the morning glory sign. Results: Initially, there were no differences in MRI-based visual rating indexes between PSP-P and PD, while PSP-RS showed a higher P/M ratio and lower M^TEGM compared with PSP-P and PD. In PD, the P/M ratio and M^TEGM remained stable with disease progression. However, the extent of changes between initial and follow-up indexes was similarly greater for both PSP-RS and PSP-P than for PD. Finally, PSP-P showed a higher P/M ratio and lower M^TEGM compared with PD in the follow-up, while PSP-RS still exhibited the most profound changes. Conclusions: Midbrain atrophy progresses differentially in patients with PSP-RS, PSP-P, and PD. Longitudinal measurements of midbrain atrophy using MRI-based visual rating indexes can help distinguish patients with PSP-P from those with PSP-RS and PD.

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“…6,[9][10][11][12][13][14][15][16][17][18][19][20][21][22] However, it takes less time to measure the anteroposterior diameter than the area. 6,[9][10][11][12][13][14][15][16][17][18][19][20][21][22] However, it takes less time to measure the anteroposterior diameter than the area.…”

Section: Introductionmentioning

confidence: 99%

“One line”: A method for differential diagnosis of parkinsonian syndromes

et al. 2019

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Background: Neurological findings are important for the differential diagnosis of Parkinson's disease (PD), multiple system atrophy with predominant parkinsonian features (MSA-P), and progressive supranuclear palsy (PSP). There is currently no fast and reliable method to distinguish these patients. Objectives:To address this, we propose a novel approach to measure midbrain and pons size using a longitudinal "one line" method from the mid-sagittal view.Methods: Structural images were acquired from 101 subjects who underwent 3.0 T MRI (20 controls, 44 PD, 20 MSA, 12 PSP, and 5 corticobasal syndrome). We measured the middle cerebellar peduncle (MCP), superior cerebellar peduncle (SCP), midbrain, and pons. Brainstem size was measured by area or length of the longitudinal axis, which we named the "one line" method. We conducted intraclass correlation coefficients to assess the extent of agreement and consistency among raters, and receiver operating characteristic curves were used to determine diagnostic accuracy.Results: Intraclass correlation coefficients (ICC) of MCP width were excellent in sagittal and axial sections while those of SCP width were moderate. There were also excellent ICCs between raters for "one line" method of the midbrain and pons, while areas showed good ICCs. "One line" method and area of the midbrain were better than SCP width for the differential diagnosis of PSP from MSA-P and PD. In contrast, there was no clearly superior measurement for differentially diagnosing MSA-P. Conclusions:The "one line" method was comparable with area for inter-rater agreement and diagnostic accuracy even though this was a simple and fast way. K E Y W O R D Sbrainstem, magnetic resonance imaging, multiple system atrophy, Parkinson's disease, progressive supranuclear palsy S U PP O RTI N G I N FO R M ATI O NAdditional supporting information may be found online in the Supporting Information section at the end of the article.How to cite this article: Sako W, Abe T, Haji S, et al. "One line": A method for differential diagnosis of parkinsonian syndromes.

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Midbrain atrophy in subcortical ischemic vascular dementia

Cited by 19 publications

References 36 publications

Late-onset multiple sclerosis presenting with cognitive dysfunction and severe cortical/infratentorial atrophy

Late-onset multiple sclerosis presenting with cognitive dysfunction and severe cortical/infratentorial atrophy

Differential Progression of Midbrain Atrophy in Parkinsonism: Longitudinal MRI Study

“One line”: A method for differential diagnosis of parkinsonian syndromes

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