Middle cerebral artery embolism and unilateral visual loss after autologous fat injection into the glabellar area.

Egido, J.; Arroyo, Ruben Casado; Marcos, Alberto; Jiménez-Alfaro, Ignacio

doi:10.1161/01.str.24.4.615

Cited by 142 publications

(73 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…A similar description was reported by Dreizen et al, although the injected material has been autologous fat 4 . In another report, Egido et al, describe middle cerebral artery embolism aside unilateral visual loss after fat injection into the glabbelar area 5 . The authors 874 Arq Neuropsiquiatr 2004;62(3-B) postulate that fat material was injected into distal branch of the ophthalmic artery, reaching choroidal and retinal circulation and send emboli into the upper division of the middle cerebral artery.…”

Section: Discussionmentioning

confidence: 98%

Blindness and total ophthalmoplegia after aesthetic polymethylmethacrylate injection: case report

Silva¹,

Curi²

2004

Arq. Neuro-Psiquiatr.

View full text Add to dashboard Cite

-Microspheres of polymethyl-methacrylate (PMMA) are exciting new soft-tissue fillers that are becoming increasing popular for facial rejuvenation. Some reports of side effects of this procedure are basically in respect to dermal reaction, with late-onset granulomatous lesion with giant cells and vacuoles. We report blindness and total ophthalmoplegia after PMMA injection into glabellar area in a healthy woman and review the literature.KEY WORDS: polymethyl-methacrylate, facial injection, blindness, ophtalmoplegia. Amaurose e oftalmoplegia total após injeção facial de polimetilmetacrilato: relato de casoRESUMO -A injeção de polimetilmetacrilato (PMMA) é prática difundida na medicina estética como medida rejuvenecedora. No entanto, a injeção facial do PMMA carreia sérios riscos, especialmente se realizada na região glabelar. Descrevemos o caso de uma mulher que imediatamente após injeção glabelar de PMMA apresentou amaurose e oftalmoplegia total, revendo ainda a literatura pertinente. PALAVRAS-CHAVE: polimetilmetacrilato, injeção facial, amaurose, oftalmoplegia.

show abstract

Section: Discussionmentioning

confidence: 98%

Blindness and total ophthalmoplegia after aesthetic polymethylmethacrylate injection: case report

Silva¹,

Curi²

2004

Arq. Neuro-Psiquiatr.

View full text Add to dashboard Cite

show abstract

“…In the following years, reports of permanent unilateral blindness from central retinal artery occlusion by injectable fillers have continued to appear in the ophthalmology and neurology literature and frequently describe stroke and skin necrosis as associated complications. Although most instances of central retinal artery occlusion and blindness resulted from injections in the nose or periorbital region, [11][12][13] some were reported with injection of fat into the nasolabial folds 14 or even the lower lip. 15 How Does an Injected Filler Cause Blindness?…”

Section: Reports Of Blindness Stroke and Skin Necrosis From Injectionsmentioning

confidence: 99%

Ischemic Stroke Caused by a Hyaluronic Acid Gel Embolism Treated with Tissue Plasminogen Activator

et al. 2017

View full text Add to dashboard Cite

In recent years, several cases of blindness, stroke, and skin necrosis have occurred after injection of soft tissue fillers. To avoid such complications, the author recommends using larger, blunt cannulas and epinephrine at the injection site, while avoiding the injection of large boluses of soft tissue filler in the face. (Aesthetic Surg J 2002;22:555-557.) I n the past 2 years in the United States, 2 cases of retinal artery occlusion have occurred in patients immediately after periorbital fat injections. Injectable fillers (fat, collagen, etc) are generally regarded as being safe, with occasional aesthetic complications; however, skin necrosis, cerebrovascular strokes, and blindness from arterial occlusion after the injection of a soft tissue filler can occur and may be underreported in the medical literature. Reports of Blindness, Stroke, and Skin Necrosis from InjectionsAs early as 1963, retinal artery occlusion from the injection of a particulate substance (steroid injections) was described. 1 Blindness from central retinal artery occlusion after steroid injections in the nose, 2-5 retrobulbar region, 6 scalp, 7 and eyelid has been reported. 8 In 1991, the Food and Drug Administration warned that adverse reactions related to injections of collagen had occurred, including "open sores, healing of the skin. . . and partial blindness." 9 Recently, the first case of partial visual field loss after an injection of Cymetra (LiteCell, Branchburg, NJ) 10 was reported.Blindness from a fat injection was first reported in 1988. 11 Few details were given, but the basic presentation was identical to the later reports. The patient experienced excruciating pain accompanied by immediate and permanent loss of vision in one eye. In the following years, reports of permanent unilateral blindness from central retinal artery occlusion by injectable fillers have continued to appear in the ophthalmology and neurology literature and frequently describe stroke and skin necrosis as associated complications. Although most instances of central retinal artery occlusion and blindness resulted from injections in the nose or periorbital region, 11-13 some were reported with injection of fat into the nasolabial folds 14 or even the lower lip. 15 How Does an Injected Filler Cause Blindness?The retinal artery and posterior ciliary arteries are proximal branches of the ophthalmic artery. Many superficial arteries of the face are distal branches of the ophthalmic artery (supraorbital, supratrochlear, dorsal nasal, angular artery of the nose). A needle or cannula used to inject a soft tissue filler can accidentally perforate the wall of one of the distal branches and enter the artery's lumen. If the tip of the needle or cannula is in the lumen of an artery when the plunger of the syringe is pressed to propel the injectable filler out of the syringe, the filler will be injected into the lumen of the cannulated artery. As more pressure is applied to the plunger, the filler displaces the arterial blood and travels as a column proximally past t...

show abstract

“…[36][37][38][39][40] This can be prevented by avoiding sharp needles and using a smaller syringe to minimize delivery pressure.…”

Section: Complicationsmentioning

confidence: 99%

Adjunctive Fat Grafting to the Upper Lid and Brow

Collar¹,

Boahene²,

Byrne³

2013

Clinics in Plastic Surgery

View full text Add to dashboard Cite

Middle cerebral artery embolism and unilateral visual loss after autologous fat injection into the glabellar area.

Cited by 142 publications

References 8 publications

Blindness and total ophthalmoplegia after aesthetic polymethylmethacrylate injection: case report

Blindness and total ophthalmoplegia after aesthetic polymethylmethacrylate injection: case report

Ischemic Stroke Caused by a Hyaluronic Acid Gel Embolism Treated with Tissue Plasminogen Activator

Adjunctive Fat Grafting to the Upper Lid and Brow

Contact Info

Product

Resources

About