Middle Cerebral Artery Stenosis in Patients with Acute Ischemic Stroke and TIA in Israel

Abstract

BACKGROUND AND PURPOSE:Middle cerebral artery stenosis is not frequent but a well-established cause of first and recurrent ischemic stroke. Our aim was to investigate middle cerebral artery stenosis in the biethnic (Jewish and Arab) population of patients with acute ischemic stroke and transient ischemic attack in northern Israel.

The association between ankle−brachial index and asymptomatic cranial‐carotid stenosis: a population‐based, cross‐sectional study of 5440 Han Chinese

“…However, they found no association between intracranial atherosclerosis and low ABI in the stroke patients, and hence suggested that a low ABI could be a predictor for ECAS but not ICAS. As expected, it was found that people with ACCS are older and have more vascular-related risk factors, similar to the reports from the other two studies [24,25].…”

Ethnicity, Cerebrovascular Diseases and Atherosclerosis-Related Syndromes and Phenomena in Northern Israel

“…On the other hand, an influence of ethnicity on examining atherosclerosis-related phenomena and syndromes in our population was limited [19]. From five examined syndromes, four-intracranial stenosis [20], presence of carotid plaques [21], carotid intima-media thickness and cerebrovascular resistance (submitted data)-were influenced only by biological factors (age and gender) or vascular risk factors. The retrospective nature of the studies included in this report should be mentioned as a limitation, which is partially overwhelmed by a large sample size and carefully performed studies protocols.…”

Association Between Steno-Occlusive Middle Cerebral Artery and Basal Ganglia Perivascular Spaces

“…Comparison of number of BG-EPVS between the affected and the unaffected side in those with only unilateral MCA stenosis or occlusion are shown in Table 4. The number of BG-EPVS was higher in the affected side than the unaffected side in patients with severe MCA stenosis (12)(13)(14) vs. 8 (6)(7)(8)(9)(10)(11), p = 0.001) and occlusion (11)(12)(13)(14) vs. 8 (5)(6)(7)(8)(9)(10)(11), p = 0.028). We found no significant difference in the number of MR-visible BG-EPVS between affected and unaffected side in patients with moderate MCA stenosis (8)(9)(10)(11) vs. 8 (5)(6)(7)(8)(9)(10)(11), p = 0.173).…”

“…Recently, the importance of understanding the pathophysiology of BG-EPVS in cerebrovascular disease is highlighted by their association with cerebral small vessel disease (CSVD), large artery atherosclerosis, and risk of stroke (7)(8)(9). Middle cerebral artery (MCA) is among the common locations of intracranial artery atherosclerosis, and MCA atherosclerosis is increasingly thought to be a significant precipitant of cerebral ischemic stroke, particularly in the Asian population (10)(11)(12). Impaired arterial stiffness (13) and increased pulsatility index (14) were found in severe MCA stenosis.…”