2006
DOI: 10.5858/2006-130-1067-mea
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Middle Ear Adenoma

Abstract: Middle ear adenoma is a benign tumor of the middle ear that can have exocrine (mucinous) and/or neuroendocrine differentiation. Early authors described a separate tumor with predominantly neuroendocrine differentiation as a middle ear carcinoid tumor, but these are now known to be the same tumor. We review the literature of this tumor, including the clinical presentation, gross pathology, histopathology, immunohistochemistry, differential diagnosis, and prognosis.

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Cited by 27 publications
(7 citation statements)
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“…What were originally thought to be independent entities, middle ear adenoma and middle ear carcinoid appear to be different stages of differentiation of the same tumor, as it possesses both epithelial and neuroendocrine differentiation. 1,2 Numerous reports have described local recurrence and regional cervical lymphatic metastasis. Interestingly, only one report of distant visceral metastasis exists in the literature.…”
Section: Introductionmentioning
confidence: 99%
See 1 more Smart Citation
“…What were originally thought to be independent entities, middle ear adenoma and middle ear carcinoid appear to be different stages of differentiation of the same tumor, as it possesses both epithelial and neuroendocrine differentiation. 1,2 Numerous reports have described local recurrence and regional cervical lymphatic metastasis. Interestingly, only one report of distant visceral metastasis exists in the literature.…”
Section: Introductionmentioning
confidence: 99%
“…First described in 1980, middle ear carcinoid is a rare clinical entity with an indolent course. What were originally thought to be independent entities, middle ear adenoma and middle ear carcinoid appear to be different stages of differentiation of the same tumor, as it possesses both epithelial and neuroendocrine differentiation 1, 2. Numerous reports have described local recurrence and regional cervical lymphatic metastasis.…”
Section: Introductionmentioning
confidence: 99%
“…MRI was performed for patients who were suspected of having a malignant tumor. The MRI findings showed higher signal of tumor than the white matter in the T1 sequence, the same signal as the gray matter in the T2 sequence, and an enhancing mass in the gadoliniumenhanced T1 sequence [6] . We reported a case of middle ear adenoma in 31 years old male patient.…”
Section: Discussionmentioning
confidence: 82%
“…1 It occurs over a wide age range, has no gender predilection. 2 Common presenting complaints are hearing loss and ear fullness on the affected side. 3 It may mimic a paraganglioma or a congenital cholesteatoma on clinical examination.…”
Section: Introductionmentioning
confidence: 99%