Midline palate perforation secondary to cocaine abuse

Velopharyngeal dysfunction from intranasal substance abuse: Case series and review of literature

“…Erosion of the velum was seen in all cases, and septal perforation was described in seven . Furthermore, oronasal fistula was a commonly reported finding . Only Deutsch and Millard documented the velar displacement and pharyngeal wall motion, which was found to be poor …”

“…Within the literature, the proposed interventions were quite varied. This included superiorly based posterior pharyngeal flap, local rotation flaps, and free flaps . One author experienced failure of the local rotation flap, which was contributed to poor viability of local tissue due to compromised vascularity .…”

“…3,4,[6][7][8][9] Furthermore, oronasal fistula was a commonly reported finding. 6,8,10 Only Deutsch and Millard documented the velar displacement and pharyngeal wall motion, which was found to be poor. 3 Within the literature, the proposed interventions were quite varied.…”

Cocaine induced midline destructive lesions

“…Continued abstinence, in fact, is an absolute requirement that patients must fulfil to consider surgical reconstruction (6) . If the patient reliably quits sniffing, medical therapy, reconstructive surgery ( Figure 2b, 5c and 5d) and prosthetics ( Figure 3c, 3d and 5b) can achieve satisfactory results (31,35,41,46,58,63,66,67,76,78,81) ; otherwise, surgical intervention is destined to failure (23,29,52,75,97) .…”

Palatal Perforation Secondary to Tuberculosis: A Case Report

“…Long standing ulcers on palate can lead to palatal perforation. Palatal perforation though rarely seen in adults but may have infectious, inflammatory, neoplastic, or traumatic cause [1]. We present here a case of palatal perforation in a 48 year old female secondary to tuberculosis which was managed successfully at our centre using greater palatine pedicled artery flap closure.…”