Midterm results of anatomic repair in a subgroup of corrected transposition

Abstract

Results of atrial switch-Rastelli procedures in this subgroup of patients with corrected transposition are satisfactory but still imperfect. Mitral regurgitation might predict a poor outcome. Long-term follow-up is necessary.

Clinical Factors Affecting Survival in Patients with Congenitally Corrected Transposition of the Great Arteries: A Systematic Review and Meta-Analysis

“…A total of 532 patients were finally enrolled, of which 83 met the combined end-point of n-SCD, SCD or SCD equivalent events, and HTX. All included trials were single-center types from seven countries [ 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 ]. The average age in the described population ranged from 9.8 to 42 years, and men accounted for 36.4–67.5%, with an average follow-up time of 5.3– 20 years.…”

“…The first group (I) includes patients after surgical correction only, while the second group (II) includes patients not operated on by any method ( Figures S1 and S2 ). After this analysis, the heterogeneity ratio decreased for subgroup I for both SVR (Inverse Variance OR 3.97 [1.41, 11.13] p = 0.009 (95% CI), I 2 = 8%) [ 9 , 10 , 14 , 18 ] and SVD (Fixed Model OR 4.69 [2.06, 10.71] p < 0.001 (95% CI), I 2 = 5%) [ 10 , 13 , 14 ]. High heterogeneity was observed in subgroup II for SVR (Inverse Variance OR 2.03 [0.01, 483.63] p = 0.8 (95% CI), I 2 = 92%), and SVD (Fixed Model OR 5.55 [1.81, 16.99] p = 0.003 (95% CI), I 2 = 82%) [ 16 , 17 ].…”

“…In patients operated in this way, dangerous ventricular arrhythmias are also observed in the short period after the procedure [ 30 ]. Tocharoenchok et al observed the population undergoing this operation, showing that only 64.2% of the subjects survived 10 years after the operation [ 18 ]. As a result, the double-switch procedure is performed only in rare, selected cases in children.…”

“…We performed a meta-analysis of the reported risk factors (Figures 2 and 3). Data on NYHA class ≥III/HF hospitalization were achievable in three publications with a total number of 122 patients [9,10,15], SVT in three types of research with a total number of 157 patients [10,16,18], at least moderate SVR in six articles with 337 patients [9,10,14,17,18], SVD in five studies with 342 patients [10,13,14,16,17], and implantation of pacemaker in three trials with 145 subjects [10,12,15] (Table S1). At least moderate NYHA class ≥III HF hospitalization (p < 0.001) and SVD (p < 0.001) were found to have a significant relationship with the combined end-point of n-SCD, SCD, and HTX.…”

Congenitally Corrected Transposition of the Great Arteries in the Adult

“…Among the cases reported, we found that 16 of them were older than 15 years of age by looking at the methods of each article. An electronic message reply was obtained from three of these authors, from three different institutions, who confirmed the operation was done in five patients, four of them with good follow-up [ 59 - 61 ] . In 2013, Talwar, in a case series that included patients over 15 years of age, reported 15 patients operated on.…”