Midtrimester abortion. Intra-amniotic instillation of hyperosmolar urea and prostaglandin F2 alpha v dilatation and evacuation

Kafrissen, Michael E.

doi:10.1001/jama.251.7.916

Cited by 18 publications

(4 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…6,7 Induction of labour by intra-amniotic instillation of saline or urea-prostaglandin F2-alpha was shown to have higher relative risks of serious complications than D&E (RR 2.6, 95% CI 1.9-3.6 and RR 1.9, 95% CI 1.2-3.1, respectively). One randomised trial comparing D&E to intra-amniotic instillation of prostaglandin F2-alpha supported these findings.…”

Section: Safety Of Dandementioning

confidence: 99%

Surgical Abortion in the Second Trimester

Lohr¹

2008

Reproductive Health Matters

View full text Add to dashboard Cite

Section: Safety Of Dandementioning

confidence: 99%

Surgical Abortion in the Second Trimester

Lohr¹

2008

Reproductive Health Matters

View full text Add to dashboard Cite

“…2 The increasing use of the surgical approach (dilation and evacuation or D and E) for second trimester abortion has reduced morbidity and mortality rates overall, but has increased the incidence of uterine perforation, subsequent intra· abdominal trauma, and the need for laparotomy to treat it. 4 Advances in ultrasonographic equipment and technique appear to offer an opportunity to reduce the incidence of serious complications associated with the D and E method of second trimester abortion.…”

mentioning

confidence: 99%

Routine intraoperative ultrasonography for second trimester abortion reduces incidence of uterine perforation.

Darney

Sweet

1989

Journal of Ultrasound in Medicine

View full text Add to dashboard Cite

Second trimester elective abortion is safest when accomplished with cervical dilation and instrumental uterine evacuation (D and E), but this procedure carries with it a risk of uterine perforation and possible intra-abdominal trauma. In order to determine if the routine use of intraoperative ultrasonography reduces the risk of this feared and serious complication, 353 elective abortions at 16 to 24 weeks gestation performed without sonography were compared to 457 in which sonography was routinely employed. All 810 operations were carried out in one clinic using the same operative technique. The routine intraoperative use of ultrasonographic imaging to guide intrauterine forceps during uterine evacuation for second trimester elective abortion resulted in a significant reduction in uterine perforation, the rate declining from 1.4% to .2%. These findings support the routine use of intraoperative ultrasonography for second trimester elective abortion to reduce the incidence of uterine perforation and make the procedure a safer one.

show abstract

“…D ilation and evacuation (D&E) is a safe procedure for pregnancy termination during the second trimester. [1][2][3][4][5][6][7][8][9][10][11][12][13] The most common complication of D&E is hemorrhage, defined as a clinical response to bleeding or estimated blood loss (EBL) greater than 500 mL. 7,[14][15][16] Uterotonics, which cause uterine contractions and decreased blood flow, are used to prevent and treat obstetric postpartum hemorrhage.…”

Section: Introductionmentioning

confidence: 99%