2022
DOI: 10.25248/reas.e9733.2022
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Mieloma múltiplo diagnosticado em paciente de um hemocentro do nordeste brasileiro: estudo de caso

Abstract: Objetivo: Discutir acerca dos achados obtidos através da análise laboratorial, assim como os fármacos administrado e monitoramento de um paciente que possui MM, atendido em um hemocentro do nordeste brasileiro. Detalhamento do caso: masculino, de 77 anos de idade, de etnia caucasiana, casado, natural de uma cidade do nordeste brasileiro, buscou o Serviço Único de Saúde (SUS), apresentando um quadro de formigamento e dormência excessiva nas extremidades dos dedos devido a vários sintomas. Logo após a realização… Show more

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Cited by 4 publications
(6 citation statements)
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“…The case reported is a localized lesion in the jaws, and we opted for biopsy and histopathology to define the diagnosis. But it is also important to evaluate the prognosis in these cases, and one factor to consider is serum lactate dehydrogenase (LDH), as a result of the reversible conversion of muscle lactic acid into pyruvic acid, this change being accomplished by the catalysis of LDH, and is found in various tissues of the human body and only a lesion characterized by cells can raise the levels of this marker, Unfortunately, it was not possible to determine the value of LDH in this patient, but other reports show that although LDH is predictive of prognosis, in some situations its values may permeate within the reference for normality, indicating that this enzyme has limited diagnostic value (DOS SANTOS et al, 2022).…”
Section: Discussionmentioning
confidence: 87%
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“…The case reported is a localized lesion in the jaws, and we opted for biopsy and histopathology to define the diagnosis. But it is also important to evaluate the prognosis in these cases, and one factor to consider is serum lactate dehydrogenase (LDH), as a result of the reversible conversion of muscle lactic acid into pyruvic acid, this change being accomplished by the catalysis of LDH, and is found in various tissues of the human body and only a lesion characterized by cells can raise the levels of this marker, Unfortunately, it was not possible to determine the value of LDH in this patient, but other reports show that although LDH is predictive of prognosis, in some situations its values may permeate within the reference for normality, indicating that this enzyme has limited diagnostic value (DOS SANTOS et al, 2022).…”
Section: Discussionmentioning
confidence: 87%
“…Factors predisposing to the development of MM include exposure to ionizing radiation and hair dyes, certain occupations (farm workers), benzene, and petroleum products, although causality is not strongly proven. With regard to family history of the disease, the presence of cases in first-degree relatives increases the risk of developing the disease by about two times (DOS SANTOS et al, 2022).…”
Section: Introductionmentioning
confidence: 99%
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“…Além disso, a hipercalcemia pode exacerbar a disfunção renal já presente em pacientes com mieloma múltiplo, contribuindo para complicações adicionais (DOS SANTOS et al, 2022).…”
Section: Resultsunclassified
“…Ocorrendo mais comumente em animais com idade entre oito e nove anos (Abreu et al, 2016). Sua etiologia, em cães, permanece desconhecida, embora em humanos, esteja relacionada com predisposição genética, infecção viral, estimulação imunológica crônica e exposição à carcinógenos (Eldin et al, 2009;Santos et al, 2022). Os sinais clínicos incluem letargia, debilidade inespecíficas e claudicação.…”
Section: Mieloma Múltiplounclassified