Miescher's Granuloma of the Face

Annular Elastolytic Giant Cell Granuloma Occurring in Covered Areas

“…Mehregan et al [4] reported 13 cases of 'Miescher's granuloma of the face', and O 'Brien [5] published a report on 13 cases of 'Actinic granuloma' on the exposed part of the body. In 1979, Hankeet al [1] designated this disease AEGCG in a report on 5 female patients with annular erythema in the face, neck and upper extremities.…”

“…Only 7 cases [6][7][8][9][10][11] have been reported in Japan, and all but the case of a 12-year-old girl [10] were males of 40 years or more of age; thus it is not likely that this dis ease appears predominantly in women [1,3,4], and there seems to be no different sex in cidence [5]. O 'Brien [5] has postulated solar elastosis as the causative factor of this dis ease; however, in 3 out of a total of 8 Japanese cases [10,11] including the present one, AEGCG occurred in covered areas.…”

Successful Therapy of Annular Elastolytic Giant Cell Granuloma with Fumaric Acid Esters

“…The term 'annular elastolytic giant cell granuloma' (AEGCG) was first proposed by Hanke et al [1], encompassing the previously described entities atypical (annular) necrobiosis lipoidica presenting on the face and scalp [2,3], Miescher's granuloma of the face [4] and actinic granuloma [5]. It is a rare granulomatous skin disease defined by clinical and histological criteria, i.e.…”

Bilateral periocular actinic granuloma in a patient with renal failure: a clinicopathologic study

“…According to O'Brien [20,22] and others [38,40], actinic damage is a necessary precondition for development of actinic granuloma. Some investigators propose a different pathogenesis for actinic granuloma-like lesions and use different names [4,7,13,18,31]. Hanke and associates [13] use the term ªannular elastolytic giant cell granulomaº, Dowling and Wilson-Jones [7] prefer ªatypical annular necrobiosis lipoidica of the face and the scalpº, and Mehregan and Altman [18] suggest ªMiescher's granuloma of the faceº.…”